通过光活性电子供体-受体复合物，以可见光促进苄基氯与硫代磺酸盐的硫代作用。

IF 3.3 2区化学 Q1 CHEMISTRY, ORGANIC The Journal of Organic Chemistry Pub Date : 2024-06-12 DOI:10.1021/acs.joc.4c00748

Chao Gong, Jialun Huang, Liuyan Cai, Yilong Yuan, Tonglv Pu, Mingjie Huang, Si-Hai Wu* and Lianhui Wang*,

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引用次数: 0

摘要

本研究通过电子供体-受体复合物策略，利用可见光促进硫代磺酸盐硫代苄基氯化物。除了高效地制备出一系列芳基苄硫化合物外，还通过应用无金属和无光催化剂方案成功地制备出了多功能硫代糖苷。初步的机理研究表明，这一转化过程涉及自由基-自由基耦合过程。

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Visible-Light-Promoted Thiolation of Benzyl Chlorides with Thiosulfonates via a Photoactive Electron Donor–Acceptor Complex

Visible-light-promoted thiolation of benzyl chlorides with thiosulfonates is disclosed via an electron donor–acceptor complex strategy. In addition to efficiently delivering a series of arylbenzylsulfide compounds, versatile thioglycosides were also successfully constructed by applying the metal- and photocatalyst-free protocol. Preliminary mechanistic studies suggest that a radical–radical coupling process was involved in this transformation.

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来源期刊

The Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： The Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.