房室传导障碍的预测因素

Carmen Marina Deutsch, E. Bădilă, Adriana Iliesiu
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摘要

房室传导障碍是指心脏电传导系统正常功能的改变,该系统通过房室结和 His-Purkinje 系统连接心房和心室。因此,心动过缓可能会出现并导致症状(头晕、意识丧失、快速性心律失常、心力衰竭现象)。识别出有可能患上房室传导障碍的患者,就能及早对风险因素进行干预,并改善预后。本综述将探讨决定房室传导障碍发生和发展的风险因素。我们将讨论传统的风险因素(年龄、性别、动脉高血压、缺血性心脏病、糖尿病、慢性肾病),以及目前正在研究的风险因素(遗传易感性和炎症标志物)。最后,我们将讨论预测房室传导障碍风险因素的局限性和挑战。
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Predictive factors of atrioventricular conduction disorders
Atrioventricular conduction disorders represent an alteration in the normal function of the heart’s electrical conduction system, a system that connects the atria and ventricles through the atrio-ventricular node and the His-Purkinje system. Consequently, bradycardia can develop and lead to the occurrence of symptoms (dizziness, loss of consciousness, tachyarrhythmias, heart failure phenomena). Identifying patients at risk of developing atrioventricular conduction disorders will allow early interventions on risk factors and improvements in prognosis. This narrative review explores the risk factors that determine the development and progression of atrioventricular conduction disorders. We will discuss traditional risk factors (age, sex, arterial hypertension, ischemic cardiac disease, diabetes, chronic kidney disease), but also risk factors that are currently being researched (genetic predisposition and inflammatory markers). Finally, we will discuss the limitations and challenges of predicting risk factors for atrioventricular conduction disorders.
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