Parthasarathy Surya, A. Sundaramanickam, Nithin Ajith
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引用次数: 0
摘要
微塑料是一种普遍存在的环境污染物,对人类健康构成潜在风险,包括罹患口腔癌。这些微小的塑料颗粒渗入各种环境壁龛,并通过摄入、吸入和皮肤接触进入人体。在胃肠道和呼吸系统等器官中检测到的微塑料可能会诱发炎症和器官功能障碍。新的研究表明,它们有可能藏匿致癌物质,导致 DNA 损伤和致癌。遗传毒性研究为风险评估和监管决策提供了依据。未来的研究应阐明微塑料与口腔癌之间的机理途径,重点关注口腔中的组织积累、炎症和 DNA 损伤。缓解策略应包括监管措施、提高公众意识的活动和牙科护理产品的进步,以应对微塑料污染带来的不断增长的健康风险。
Comment on “cancer may be induced by microplastics-sorbed polycyclic aromatic hydrocarbons?”
Microplastics, pervasive environmental contaminants, pose a potential risk to human health, including the development of oral carcinoma. These minute plastic particles infiltrate various environmental niches and enter the human body through ingestion, inhalation, and dermal exposure. Detected in organs such as the gastrointestinal tract and respiratory system, microplastics may induce inflammation and organ dysfunction. Emerging research suggests their potential to harbor carcinogenic substances, leading to DNA damage and carcinogenesis. Genotoxicity studies inform risk assessment and regulatory decisions. Future research should elucidate the mechanistic pathways linking microplastics to oral carcinoma, focusing on tissue accumulation, inflammation, and DNA damage in the oral cavity. Mitigation strategies should encompass regulatory measures, public awareness campaigns, and advancements in dental care products to address the burgeoning health risks posed by microplastic pollution.