2023 年阿塞利奖得主:一个淋巴疯子的生活与时代》。

Lymphology Pub Date : 2023-01-01
D G Jackson
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引用次数: 0

摘要

获得科学奖总是令人欣喜的荣誉,而在2023年获得阿塞利奖尤其令人惊喜。我的研究小组在牛津大学开展的研究发现了淋巴内皮标志物LYVE-1,并发现它是控制免疫细胞和转移性肿瘤细胞进入外周组织淋巴毛细血管的关键受体。作为一名基础科学家和淋巴学领域的后来者,我希望基础研究和临床研究之间更紧密的合作将有助于解释淋巴管的复杂运作,并改善备受忽视的淋巴疾病患者的状况。
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Aselli Award Winner 2023: The Life and Times of a Lymphomaniac.

Winning a scientific prize is always a welcome honor and receiving the Aselli Award in 2023 was a particularly pleasant surprise. The following text provides a brief summary of the research carried out by my group in Oxford that led to the discovery of the lymphatic endo-thelial marker LYVE-1 and its emerging role as a pivotal receptor controlling the entry of immune cells and metastatic tumor cells to lymphatic capillaries in peripheral tissues. As a basic scientist and relatively late comer to the field of lymphology, my hope is that a closer partnership of basic and clinical research will help explain the intricate workings of the lymphatics and improve the picture for patients suffering from much neglected lymphatic disorders.

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