使用一氧化二氮的临床表现：病例报告和文献综述。

IF 1.6 4区医学 Q3 SUBSTANCE ABUSE Journal of Addictive Diseases Pub Date : 2024-06-24 DOI:10.1080/10550887.2024.2369744

Nicholas Nelson, Alejandro Diaz, Ghita Bouzarif, Jenna Chen, Nirmita Doshi, Adam Mortimer, Indhu Subramanian

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引用次数: 0

摘要

在医学上，一氧化二氮被用作麻醉剂；在食品工业中，一氧化二氮被用作调味品的推进剂；在娱乐方面，一氧化二氮具有兴奋和解离作用。我们报告了三例滥用一氧化二氮导致严重症状性钴胺素（维生素 B12）缺乏症的病例，在这些病例中，我们观察到了使用一氧化二氮本身的迹象以及中毒迹象，包括掌骨上的特征性胼胝和冻伤。这些体征可能有助于临床医生识别一氧化二氮的使用，并及时诊断一氧化二氮中毒。

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Clinical signs of nitrous oxide use: case report and review of the literature.

Nitrous oxide is used medically as an anesthetic agent; in the food industry as a propellant for condiments; and recreationally for its euphoric and dissociative effects. We report three cases of nitrous oxide misuse causing severe, symptomatic cobalamin (vitamin B12) deficiency in which signs of nitrous oxide use per se, as well as signs of toxicity, were observed, including characteristic palmar calluses over the metacarpal heads, and frostbite. These signs may assist clinicians in the recognition of nitrous oxide use and the timely diagnosis of nitrous oxide toxicity.

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来源期刊

Journal of Addictive Diseases SUBSTANCE ABUSE-

CiteScore

4.30

自引率

4.30%

发文量

期刊介绍： The Journal of Addictive Diseases is an essential, comprehensive resource covering the full range of addictions for today"s addiction professional. This in-depth, practical journal helps you stay on top of the vital issues and the clinical skills necessary to ensure effective practice. The latest research, treatments, and public policy issues in addiction medicine are presented in a fully integrated, multi-specialty perspective. Top researchers and respected leaders in addiction issues share their knowledge and insights to keep you up-to-date on the most important research and practical applications.