目前的共孕咨询实践:关于受早期乳腺癌影响的年轻女性生育力保存和治疗后怀孕的最新证据。

IF 2.9 3区 医学 Q2 ONCOLOGY Expert Review of Anticancer Therapy Pub Date : 2024-09-01 Epub Date: 2024-07-09 DOI:10.1080/14737140.2024.2372337
Luca Arecco, Roberto Borea, Isotta Martha Magaton, Kristina Janković, Elene Mariamizde, Mihaela Stana, Graziana Scavone, Silvia Ottonello, Stefano Spinaci, Carlo Genova, Evandro de Azambuja, Matteo Lambertini
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引用次数: 0

摘要

简介过去几年中,抗癌治疗为提高乳腺癌治愈率做出了巨大贡献;然而,抗癌治疗也可能导致中长期副作用,包括性腺毒性和影响年轻女性的生育能力。对于那些在确诊癌症时尚未完成计划生育的年轻患者来说,肿瘤不孕症是一个至关重要的问题:本综述旨在涵盖肿瘤不孕症领域的所有最新可用证据,包括目前在乳腺癌治愈性治疗中采用的抗癌疗法的性腺毒性、可用的生育力保护策略以及在完成抗癌治疗后怀孕的可行性:在过去几年中,针对年轻乳腺癌女性患者的辅助生育治疗取得了重大进展。根据现有证据,每一位新确诊乳腺癌的年轻女性在开始任何抗癌治疗之前,都应接受适当、完整的辅助生育咨询,以增加未来怀孕的机会。
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Current practices in oncofertility counseling: updated evidence on fertility preservation and post-treatment pregnancies in young women affected by early breast cancer.

Introduction: Anticancer treatments have significantly contributed to increasing cure rates of breast cancer in the last years; however, they can also lead to short- and long-term side effects, including gonadotoxicity, and compromised fertility in young women. Oncofertility is a crucial issue for young patients who have not yet completed their family planning at the time of cancer diagnosis.

Areas covered: This review aims to cover all the latest available evidence in the field of oncofertility, including the gonadotoxicity of currently adopted anticancer therapies in the curative breast cancer setting, the available strategies for fertility preservation and the feasibility of achieving a pregnancy following anticancer treatment completion.

Expert opinion: Over the past years, a significant progress has been made in oncofertility care for young women with breast cancer. In the context of the currently available evidence, every young woman with newly diagnosed breast cancer should receive a proper and complete oncofertility counseling before starting any anticancer treatment to increase her chances of future pregnancies.

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来源期刊
CiteScore
5.10
自引率
3.00%
发文量
100
审稿时长
4-8 weeks
期刊介绍: Expert Review of Anticancer Therapy (ISSN 1473-7140) provides expert appraisal and commentary on the major trends in cancer care and highlights the performance of new therapeutic and diagnostic approaches. Coverage includes tumor management, novel medicines, anticancer agents and chemotherapy, biological therapy, cancer vaccines, therapeutic indications, biomarkers and diagnostics, and treatment guidelines. All articles are subject to rigorous peer-review, and the journal makes an essential contribution to decision-making in cancer care. Comprehensive coverage in each review is complemented by the unique Expert Review format and includes the following sections: Expert Opinion - a personal view of the data presented in the article, a discussion on the developments that are likely to be important in the future, and the avenues of research likely to become exciting as further studies yield more detailed results Article Highlights – an executive summary of the author’s most critical points.
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