在水溶性金属配体双功能铱催化剂催化下通过无受体脱氢在水中将甘油选择性转化为乳酸

IF 4.3 2区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR Inorganic Chemistry Pub Date : 2024-07-02 DOI:10.1021/acs.inorgchem.4c01617

Xiangchao Xu, Heng You, Beixuan Dong, Yiqian He, Feng Li

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引用次数: 0

摘要

通过无受体脱氢，开发出了一种在水中将生物柴油生产过程中的主要副产品甘油选择性转化为乳酸的高效方法。在水溶性[Cp*Ir(6,6'-(OH)2-2,2'-bpy)(H2O)][OTf]2（0.1 摩尔%）和 KOH（1.1 等量）的存在下，反应在 120 °C 下进行 24 小时，得到所需产物，产率大于 99%，选择性大于 99%。研究证实，配体中的羟基官能团对铱配合物的活性至关重要。此外，还进行了密度泛函理论计算和机理实验。

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Selective Conversion of Glycerol to Lactic Acid in Water via Acceptorless Dehydrogenation Catalyzed by a Water-Soluble Metal-Ligand Bifunctional Iridium Catalyst.

An efficient method for the selective conversion of glycerol, the major byproduct of the biodiesel manufacturing process, to lactic acid in water via acceptorless dehydrogenation has been developed. In the presence of a water-soluble [Cp*Ir(6,6'-(OH)₂-2,2'-bpy)(H₂O)][OTf]₂ (0.1 mol %) and KOH (1.1 equiv), the reaction proceeded at 120 °C for 24 h to afford the desired product in >99% yield with >99% selectivity. It was confirmed that OH functional groups in the ligand were crucial for the activity of the iridium complex. Furthermore, density functional theory calculations and mechanistic experiments were also undertaken.

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来源期刊

Inorganic Chemistry 化学-无机化学与核化学

CiteScore

7.60

自引率

13.00%

发文量

1960

审稿时长

1.9 months

期刊介绍： Inorganic Chemistry publishes fundamental studies in all phases of inorganic chemistry. Coverage includes experimental and theoretical reports on quantitative studies of structure and thermodynamics, kinetics, mechanisms of inorganic reactions, bioinorganic chemistry, and relevant aspects of organometallic chemistry, solid-state phenomena, and chemical bonding theory. Emphasis is placed on the synthesis, structure, thermodynamics, reactivity, spectroscopy, and bonding properties of significant new and known compounds.