分析南非两条河流中的水葫芦植物,以检测七种药物及其代谢物。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2024-07-04 DOI:10.1002/elps.202400101
Markus Himmelsbach, Franz Mlynek, Wolfgang Buchberger, Lawrence Madikizela, Christian W Klampfl
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引用次数: 0

摘要

对从南非两条河流中采集的布袋莲植物(Eichhornia crassipes Mart.)进行了分析,以研究它们是否适合用于判断水中是否含有药物。因此,可以检测到多种药物,包括阿米替林、阿替洛尔、西酞普兰、奥芬那定、利多卡因、替米沙坦和曲马多。特别是后一种物质,在水生植物中检测到的浓度相对较高(超过 5000 纳克 g-1 干植物材料)。随后,还对植物提取物中的药物转化产物进行了筛选,从而初步确定了一系列相一代谢物。
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Analyzing water hyacinth plants from two South African rivers for the detection of seven pharmaceuticals and their metabolites.

Water hyacinth plants (Eichhornia crassipes Mart.) collected from two South African rivers were analyzed in order to investigate their suitability for judging the presence of pharmaceuticals in the water. Thereby, a number of drugs, including amitriptyline, atenolol, citalopram, orphenadrine, lidocaine, telmisartan, and tramadol, could be detected. Particularly for the latter substance, relatively high concentrations (more than 5000 ng g-1 dry plant material) were detected in the water plants. Subsequently, the plant extracts were also screened for drug-derived transformation products, whereby a series of phase-one metabolites could be tentatively identified.

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4.30%
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