Theoretico-conceptual frameworks for psychoneuroimmunology

This article examines the theoretico/conceptual foundations of psychoneuroimmunology (PNI). A materialist/mechanist foundation appears to predominate in the field. We suggest that a complementarity framework might be a better lens for examining different neuro-immune and psychological connections, including psychological function and dysfunction as related to neurophysiological and immunological dynamics. Through this examination, it is hypothesized that PNI would best work with a complementarity foundation, as opposed to materialism, mechanism, or dualistic interactionism. At the very least, this examination gives us a deeper respect for showing the complexity of consciousness and health. An appropriate view of the mind-body relation should provide a sound theoretical framework for PNI research serving to bridge new dynamics between the neuro-immune and the psychological.