老年人紧急血液透析对肾脏和患者的影响:一项回顾性队列研究。

IF 1.8 4区 医学 Q3 UROLOGY & NEPHROLOGY International Urology and Nephrology Pub Date : 2024-12-01 Epub Date: 2024-07-09 DOI:10.1007/s11255-024-04145-y
Zeynep Toker Dincer, Mevlut Tamer Dincer, Serkan Feyyaz Yalin, Sinan Trabulus, Nurhan Seyahi, Mehmet Riza Altiparmak
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引用次数: 0

摘要

目的:老龄人口(通常指 65 岁及以上人群)罹患肾脏相关疾病的风险增加。本研究调查了老年人群中的紧急透析情况,重点关注适应症、临床和实验室检查结果、肾脏状况和死亡率:方法:回顾性研究了在一家三级大学医院接受紧急透析的 442 名老年患者(≥ 65 岁)的数据。对人口统计学、合并症、紧急透析适应症、临床表现、方法、并发症、透析前后状况和随访情况进行了评估:结果:74.9%的患者有慢性肾脏病(CKD)病史。开始紧急透析的主要原因是高血容量(43.7%)和尿毒症症状(29.2%)。低血压是最常见的透析相关并发症(34.4%)。死亡率为34.6%;在幸存者中,15.2%的人实现了肾功能完全恢复,而32.5%和52.3%的人分别发展为透析非依赖型和依赖型慢性肾脏病。在多变量分析中发现,入院时的血尿素、血清钠、平均动脉压、呼吸困难、呼吸急促和心动过速与死亡率有关:我们的研究为老年人群的紧急透析挑战提供了见解,强调了个性化干预和进一步研究的必要性,以改善这一日益增长的人群的护理和治疗效果。
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Renal and patient outcomes of emergency hemodialysis in elderly individuals: a retrospective cohort study.

Purpose: The aging population, commonly defined as individuals aged 65 and above, faces an increased risk of kidney-related diseases. This study investigates emergency dialysis in the elderly population, focusing on indications, clinical and laboratory findings, renal status, and mortality rates.

Methods: The data of 442 elderly patients (≥ 65 years old) who underwent emergency dialysis at a tertiary university hospital were retrospectively examined. Demographics, comorbidities, emergency dialysis indications, clinical presentation, method, complications, pre/post-dialysis status, and follow-up were assessed.

Results: 74.9% of the patients had a history of chronic kidney disease (CKD). Emergency dialysis was mainly initiated due to hypervolemia (43.7%) and uremic symptoms (29.2%). Hypotension was the most common dialysis-related complication (34.4%). The mortality rate was 34.6%; among the survivors, 15.2% achieved complete renal recovery, while 32.5% and 52.3% developed dialysis-independent and -dependent CKD, respectively. In multivariate analysis, blood urea, serum sodium, mean arterial pressure, dyspnea, tachypnea, and tachycardia on admission were found to be associated with mortality.

Conclusion: Our study provides insights into emergency dialysis challenges in the elderly population, emphasizing the need for personalized interventions and further research to improve care and outcomes in this growing demographic.

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来源期刊
International Urology and Nephrology
International Urology and Nephrology 医学-泌尿学与肾脏学
CiteScore
3.40
自引率
5.00%
发文量
329
审稿时长
1.7 months
期刊介绍: International Urology and Nephrology publishes original papers on a broad range of topics in urology, nephrology and andrology. The journal integrates papers originating from clinical practice.
期刊最新文献
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