一种罕见的模仿周身淋巴管瘤的转移性乳腺癌。

IF 1.6 4区 医学 Q3 DERMATOLOGY Journal of Cutaneous Pathology Pub Date : 2024-07-09 DOI:10.1111/cup.14688
Zacaria Jr. B. Pario, Ma Flordeliz Abad-Casintahan, Jonnie Rose Louise R. Wee, Melissa Rinne V. See, Karen Andrea D. Cadacio
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引用次数: 0

摘要

皮肤转移很罕见,但可能预示着内部恶性肿瘤已到晚期,或之前治疗过的恶性肿瘤复发,通常预后较差。由于皮肤转移瘤的临床表现多变且无特异性,可能会与其他良性疾病相混淆,因此也会给诊断带来困难。我们报告了一例 48 岁女性的病例,她躯干上的红斑丘疹和水泡病史长达 4 年,模仿周身淋巴管瘤。皮肤活检和免疫组化结果与乳腺癌的皮肤转移一致。皮肤转移的表现形式多种多样。高怀疑指数和低皮肤活检门槛对早期诊断和治疗至关重要。组织病理学评估将有助于确定皮肤转移瘤的来源,并对治疗效果产生重大影响。
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A rare form of metastatic breast carcinoma mimicking lymphangioma circumscriptum

Cutaneous metastasis is rare but may indicate an advanced internal malignancy or a recurrence of a previously treated one and is usually associated with a poor prognosis. They may also pose a diagnostic problem as the clinical manifestations are variable and non-specific, which could mimic other benign conditions. We report a case of a 48-year-old female who presented with a 4-year history of erythematous papules and vesicles on the trunk mimicking lymphangioma circumscriptum. Skin biopsy and immunohistochemistry were consistent with cutaneous metastasis from breast carcinoma. Cutaneous metastasis presents in a variety of patterns. A high index of suspicion and a low threshold for skin biopsy are paramount to the early diagnosis and treatment. A histopathologic evaluation will help identify the origin of the cutaneous metastasis and can significantly affect the outcome of the treatment.

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来源期刊
CiteScore
3.20
自引率
5.90%
发文量
174
审稿时长
3-8 weeks
期刊介绍: Journal of Cutaneous Pathology publishes manuscripts broadly relevant to diseases of the skin and mucosae, with the aims of advancing scientific knowledge regarding dermatopathology and enhancing the communication between clinical practitioners and research scientists. Original scientific manuscripts on diagnostic and experimental cutaneous pathology are especially desirable. Timely, pertinent review articles also will be given high priority. Manuscripts based on light, fluorescence, and electron microscopy, histochemistry, immunology, molecular biology, and genetics, as well as allied sciences, are all welcome, provided their principal focus is on cutaneous pathology. Publication time will be kept as short as possible, ensuring that articles will be quickly available to all interested in this speciality.
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