利用从植物中分离的益生菌再加工药草残留物及其对腹泻的有益作用

IF 4.6 Q1 CHEMISTRY, APPLIED Food Hydrocolloids for Health Pub Date : 2024-06-20 DOI:10.1016/j.fhfh.2024.100181
Samima Yeasmin , Abu Naser Md Nayeem , Anjumanara khatun , ABM Ashraful , Muhsi Faiaz , Shumaia Parvin , Most. Afia Akhtar , Md Aziz Abdur Rahman , Md Abu Reza , Athanasios Alexiou , Marios Papadakis , Nermeen N. Welson , Mohamed H. Mahmoud , Gaber El-Saber Batiha , Ronok Zahan
{"title":"利用从植物中分离的益生菌再加工药草残留物及其对腹泻的有益作用","authors":"Samima Yeasmin ,&nbsp;Abu Naser Md Nayeem ,&nbsp;Anjumanara khatun ,&nbsp;ABM Ashraful ,&nbsp;Muhsi Faiaz ,&nbsp;Shumaia Parvin ,&nbsp;Most. Afia Akhtar ,&nbsp;Md Aziz Abdur Rahman ,&nbsp;Md Abu Reza ,&nbsp;Athanasios Alexiou ,&nbsp;Marios Papadakis ,&nbsp;Nermeen N. Welson ,&nbsp;Mohamed H. Mahmoud ,&nbsp;Gaber El-Saber Batiha ,&nbsp;Ronok Zahan","doi":"10.1016/j.fhfh.2024.100181","DOIUrl":null,"url":null,"abstract":"<div><p>This study aims to use hot aqueous extract of herbal residue (HRE) to enhance bacterial growth and possess anti-diarrheal effects. In this study, lactobacillus species <em>L. brevis</em> (SAM-1), <em>Lactobacillus plantarum</em> (SAM-2), and <em>Lactobacillus herbinensis</em> (SAM-3) were isolated from date palm sap (collected in winter season). Square Pharmaceuticals PLC, Bangladesh provided herbal residues ‘Adovas’ which is non-sedating herbal cough syrup with sixteen common herbs including Adhatoda vasica. In our observation, HRE increased the number of colonies in MRS media. In the anti-diarrheal study by castor oil and magnesium sulphate-induced diarrheal mouse model, SAM-1 and 2 with or without HRE showed almost similar results. After initial morphological characterization, tests such as resistance to low pH, bile salt and survival capability in gastric simulated fluid (GSF) were performed to confirm them as a probiotic candidate. All three isolates were gram-positive bacteria and could grow in a mesophilic range of temperatures. The isolates were catalase-negative and were able to coagulate milk after overnight incubation. As the isolates exhibited resistance to low pH and could tolerate bile salts, they may survive in the stomach and intestine, thus making them a promising probiotic candidate. The isolated probiotics and HRE inhibited diarrheal and restored the body's electrolytes. Interestingly, SAM-2 showed higher efficacy than the standard drug (Loperamide), while SAM-1 showed a similar effect and SAM-3, had less effect than Loperamide. The findings suggest that probiotics and herbal residue could contribute to diarrhoeal disease prevention, which might be an alternative to a synthetic standard drug (Loperamide).</p></div>","PeriodicalId":12385,"journal":{"name":"Food Hydrocolloids for Health","volume":"6 ","pages":"Article 100181"},"PeriodicalIF":4.6000,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667025924000062/pdfft?md5=74ade19406a0f4ff223016a68aac7412&pid=1-s2.0-S2667025924000062-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Re-processing of pharmaceutical herb residues using isolated probiotics from plant sources and their beneficial effects on diarrhea\",\"authors\":\"Samima Yeasmin ,&nbsp;Abu Naser Md Nayeem ,&nbsp;Anjumanara khatun ,&nbsp;ABM Ashraful ,&nbsp;Muhsi Faiaz ,&nbsp;Shumaia Parvin ,&nbsp;Most. Afia Akhtar ,&nbsp;Md Aziz Abdur Rahman ,&nbsp;Md Abu Reza ,&nbsp;Athanasios Alexiou ,&nbsp;Marios Papadakis ,&nbsp;Nermeen N. Welson ,&nbsp;Mohamed H. Mahmoud ,&nbsp;Gaber El-Saber Batiha ,&nbsp;Ronok Zahan\",\"doi\":\"10.1016/j.fhfh.2024.100181\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>This study aims to use hot aqueous extract of herbal residue (HRE) to enhance bacterial growth and possess anti-diarrheal effects. In this study, lactobacillus species <em>L. brevis</em> (SAM-1), <em>Lactobacillus plantarum</em> (SAM-2), and <em>Lactobacillus herbinensis</em> (SAM-3) were isolated from date palm sap (collected in winter season). Square Pharmaceuticals PLC, Bangladesh provided herbal residues ‘Adovas’ which is non-sedating herbal cough syrup with sixteen common herbs including Adhatoda vasica. In our observation, HRE increased the number of colonies in MRS media. In the anti-diarrheal study by castor oil and magnesium sulphate-induced diarrheal mouse model, SAM-1 and 2 with or without HRE showed almost similar results. After initial morphological characterization, tests such as resistance to low pH, bile salt and survival capability in gastric simulated fluid (GSF) were performed to confirm them as a probiotic candidate. All three isolates were gram-positive bacteria and could grow in a mesophilic range of temperatures. The isolates were catalase-negative and were able to coagulate milk after overnight incubation. As the isolates exhibited resistance to low pH and could tolerate bile salts, they may survive in the stomach and intestine, thus making them a promising probiotic candidate. The isolated probiotics and HRE inhibited diarrheal and restored the body's electrolytes. Interestingly, SAM-2 showed higher efficacy than the standard drug (Loperamide), while SAM-1 showed a similar effect and SAM-3, had less effect than Loperamide. The findings suggest that probiotics and herbal residue could contribute to diarrhoeal disease prevention, which might be an alternative to a synthetic standard drug (Loperamide).</p></div>\",\"PeriodicalId\":12385,\"journal\":{\"name\":\"Food Hydrocolloids for Health\",\"volume\":\"6 \",\"pages\":\"Article 100181\"},\"PeriodicalIF\":4.6000,\"publicationDate\":\"2024-06-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2667025924000062/pdfft?md5=74ade19406a0f4ff223016a68aac7412&pid=1-s2.0-S2667025924000062-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food Hydrocolloids for Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667025924000062\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Hydrocolloids for Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667025924000062","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0

摘要

本研究旨在利用草药残渣的热水溶液提取物(HRE)来促进细菌生长,并具有止泻作用。本研究从枣椰树汁液(冬季采集)中分离出乳酸杆菌 L. brevis(SAM-1)、植物乳杆菌 Lactobacillus plantarum(SAM-2)和草本乳杆菌 Lactobacillus herbinensis(SAM-3)。孟加拉国 Square Pharmaceuticals PLC 公司提供的草药残留物 "Adovas "是一种非镇静型草药止咳糖浆,含有 16 种常见草药,其中包括 Adhatoda vasica。根据我们的观察,HRE 增加了 MRS 培养基中的菌落数量。在用蓖麻油和硫酸镁诱导的腹泻小鼠模型进行的抗腹泻研究中,含有或不含 HRE 的 SAM-1 和 2 显示出几乎相似的结果。在初步形态特征鉴定之后,又进行了耐低 pH 值、耐胆盐和在胃模拟液(GSF)中存活能力等测试,以确认它们是候选益生菌。这三种分离物均为革兰氏阳性菌,可在中嗜酸性温度范围内生长。分离菌的催化酶阴性,在过夜培养后能凝固牛奶。由于分离出的益生菌耐低 pH 值,并能耐受胆汁盐,因此可在胃肠中存活,是一种很有前途的候选益生菌。分离出的益生菌和 HRE 可抑制腹泻并恢复人体电解质。有趣的是,SAM-2 的功效高于标准药物(洛哌丁胺),而 SAM-1 的功效与之相似,SAM-3 的功效则低于洛哌丁胺。研究结果表明,益生菌和草药残留物有助于预防腹泻疾病,可作为合成标准药物(洛哌丁胺)的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Re-processing of pharmaceutical herb residues using isolated probiotics from plant sources and their beneficial effects on diarrhea

This study aims to use hot aqueous extract of herbal residue (HRE) to enhance bacterial growth and possess anti-diarrheal effects. In this study, lactobacillus species L. brevis (SAM-1), Lactobacillus plantarum (SAM-2), and Lactobacillus herbinensis (SAM-3) were isolated from date palm sap (collected in winter season). Square Pharmaceuticals PLC, Bangladesh provided herbal residues ‘Adovas’ which is non-sedating herbal cough syrup with sixteen common herbs including Adhatoda vasica. In our observation, HRE increased the number of colonies in MRS media. In the anti-diarrheal study by castor oil and magnesium sulphate-induced diarrheal mouse model, SAM-1 and 2 with or without HRE showed almost similar results. After initial morphological characterization, tests such as resistance to low pH, bile salt and survival capability in gastric simulated fluid (GSF) were performed to confirm them as a probiotic candidate. All three isolates were gram-positive bacteria and could grow in a mesophilic range of temperatures. The isolates were catalase-negative and were able to coagulate milk after overnight incubation. As the isolates exhibited resistance to low pH and could tolerate bile salts, they may survive in the stomach and intestine, thus making them a promising probiotic candidate. The isolated probiotics and HRE inhibited diarrheal and restored the body's electrolytes. Interestingly, SAM-2 showed higher efficacy than the standard drug (Loperamide), while SAM-1 showed a similar effect and SAM-3, had less effect than Loperamide. The findings suggest that probiotics and herbal residue could contribute to diarrhoeal disease prevention, which might be an alternative to a synthetic standard drug (Loperamide).

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
4.50
自引率
0.00%
发文量
0
审稿时长
61 days
期刊最新文献
Encapsulation of yarrow phenolic compounds in lupin protein nanoemulsions increases stability during gastrointestinal transit and delivery in the colon Pectin oligosaccharides from Citri Reticulatae Pericarpium ‘Chachi’ promote wound healing in HaCaT keratinocytes by enhancing cell proliferation and migration Green synthesis of silver nanoparticles from mulberry leaf through hot melt extrusion: Enhanced antioxidant, antibacterial, anti-inflammatory, antidiabetic, and anticancer properties Silkworm pupae protein-based film incorporated with Catharanthus roseus leaf extract-based nanoparticles enhanced the lipid stability and microbial quality of cheddar cheese Re-processing of pharmaceutical herb residues using isolated probiotics from plant sources and their beneficial effects on diarrhea
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1