Medohar Arka 对 Sthaulya(超重)的疗效 - 单盲安慰剂对照临床研究

IF 0.1 Q4 MEDICINE, RESEARCH & EXPERIMENTAL International Journal of Ayurvedic Medicine Pub Date : 2024-07-10 DOI:10.47552/ijam.v15i2.4503
Twinkle Joshi, Vaishali Kuchewar, Aman Chhabra
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引用次数: 0

摘要

在阿育吠陀中,Sthaulya 是由 Meda 过度积聚导致 Sphik、Udara 和 Stana 出现下垂的 santarpanothha vyadhi。它可能与超重或肥胖有关。肥胖的特点是脂肪细胞体积或数量增大,导致脂肪组织异常增生,以 BMI 表示,24.9 kg/m2 至 29.9 kg/m2 表示超重,大于 30 kg/m2 表示肥胖。已对 medohar guggulu、navaka guggulu 等药物进行了研究,但 Medohar Arka 的研究相对较少。它是 Ras Tantra Saara 和 Siddha Prayoga Sangraha 描述的一种用于治疗肥胖症的低成本药物。材料与方法--研究包括 66 名参与者,年龄在 20-50 岁之间,性别不限,体重在 25-30 kg/m2 之间。M 组接受 Medohar Arka 15 毫升的治疗,每天两次,饭前与等量的水一起服用;P 组接受安慰剂 250 毫克的治疗,每天两次,饭前与等量的水一起服用,连续 90 天。对两组患者都建议采取饮食疗法和 30 分钟快走疗法。第 0 天和第 90 天(治疗结束)进行评估。对参与者的体重指数、腰臀比(WHR)和中臂围(MAC)等客观参数进行了评估。经比较,Medohar arka 组的体重指数、腰臀比和中臂围均有明显改善。结论:Medohar Arka 能有效控制超重。可对肥胖患者进行进一步研究,以推广使用这种药物。
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Efficacy of Medohar Arka in Sthaulya (Overweight) – A single blind placebo controlled clinical study
In Ayurveda, Sthaulya is santarpanothha vyadhi caused by excessive accumulation of Meda resulting in pendulous appearance of Sphik, Udara and Stana. It can be correlated with overweight or obesity. Obesity is characterized by abnormal growth of adipose tissue due to enlargement of fat cell size or number which is expressed in BMI, 24.9 kg/m2 to 29.9 kg/m2 indicates overweight and >30 kg/m2 indicates obesity. Studies have been conducted on medications like medohar guggulu, navaka guggulu but Medohar Arka was relatively unexplored. It is a low cost medicine described by Ras Tantra Saara and Siddha Prayoga Sangraha for sthaulya. Material and Methods-Study comprised of 66 participants between age group of 20-50 years, either sex, having B.M.I. between 25-30 kg/m2. Group M was treated with Medohar Arka 15ml twice daily before food with equal amount of water whereas Group P was treated with Placebo 250 mg twice daily before food with equal amount water for 90 days. Pathyapathya and vyayama was advised to both groups in the form of Ahar (Diet) and Vihar(30 min brisk walk). Assessment was done on day 0 and day 90 (completion of treatment). Participants were assessed for objective parameters like Body Mass Index, Waist Hip Ratio(WHR) and Mid Arm circumference(MAC). On comparing both the groups, statistically significant improvement was observed in Body Mass Index, Waist Hip Ratio, Mid Arm circumference in Medohar arka group. Conclusion- Medohar Arka was effective in managing overweight. Further study could be conducted on obese patients for generalized use of this medicine.
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来源期刊
International Journal of Ayurvedic Medicine
International Journal of Ayurvedic Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
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50.00%
发文量
87
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