Changning Yu , Haoxiang Xu , Jieyuan Jiang , Zhigang Tan , Xianfeng Peng , Song Liu , Chengbo Yang
{"title":"高饲养密度下补充苯甲酸或苯并钙-50 对罗斯 308 混性别鸡生长性能和肠道健康的影响","authors":"Changning Yu , Haoxiang Xu , Jieyuan Jiang , Zhigang Tan , Xianfeng Peng , Song Liu , Chengbo Yang","doi":"10.1016/j.japr.2024.100454","DOIUrl":null,"url":null,"abstract":"<div><p>An experiment was conducted to evaluate the impacts of dietary supplementation with unprotected benzoic acid (<strong>BA</strong>) or benzocal-50 (protected BA) on the growth performance and intestinal health in mixed-sex Ross 308 broilers under a high stocking density. A total of 768 one-d-old mixed-sex Ross 308 chickens (BW: 43.52 ± 0.68 g) were randomly allotted to 4 treatments (6 replicates with 32 broilers in each): 1) basal diet (NC); 2) basal diet with 30 mg/kg of avilamycin (PC); 3) basal diet with 1,000 mg/kg of BA (PBA); and 4) basal diet with benzocal-50 (330, 330, and 300 mg/kg in the starter (d 1-14), grower (d 15–28), and finisher (d 29–41) phases) (EBA). The normal stocking density during the finisher phase for broilers is 25.0 kg BW/m², but this study used a density of 29.0 kg BW/m² for a high stocking density. The results revealed an increase in the ADG of the EBA treatment compared to the PBA treatment during d 8 to 14 (<em>P</em> < 0.05). In the grower (d 15–28) and finisher (d 29–41) phases, chickens fed the EBA treatment exhibited lower intestinal digesta pH values than those in the NC treatment (<em>P</em> < 0.05). Moreover, the EBA treatment displayed greater AID of dry matter and crude protein than the PC treatment (<em>P</em> < 0.05). The EBA treatment resulted in an upregulation of sodium-dependent neutral amino acid transporter and peptide transporter (<strong>PEPT1</strong>) mRNA expressions in the jejunum on d 14, an increased sodium-glucose transport protein 1 mRNA expression in the jejunum on d 28, and enhanced PEPT1 mRNA expression in the jejunum on d 41, when compared to the NC treatment (<em>P</em> < 0.05). Moreover, the EBA treatment improved cadherin 1 mRNA expression in the jejunum on d 28 than the NC and PC treatments (<em>P</em> < 0.05). Overall, supplementing benzocal-50 to broilers under a high stocking density led to a decrease in gut pH, contributing to reduced fecal score and an overall enhancement in the gut barrier function.</p></div>","PeriodicalId":15240,"journal":{"name":"Journal of Applied Poultry Research","volume":"33 3","pages":"Article 100454"},"PeriodicalIF":1.6000,"publicationDate":"2024-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1056617124000539/pdfft?md5=65de4873c012fbcfa3979afddbee9a8d&pid=1-s2.0-S1056617124000539-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Effects of benzoic acid or benzocal-50 supplementation on growth performance and intestinal health in mixed-sex Ross 308 chickens under a high stocking density\",\"authors\":\"Changning Yu , Haoxiang Xu , Jieyuan Jiang , Zhigang Tan , Xianfeng Peng , Song Liu , Chengbo Yang\",\"doi\":\"10.1016/j.japr.2024.100454\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>An experiment was conducted to evaluate the impacts of dietary supplementation with unprotected benzoic acid (<strong>BA</strong>) or benzocal-50 (protected BA) on the growth performance and intestinal health in mixed-sex Ross 308 broilers under a high stocking density. A total of 768 one-d-old mixed-sex Ross 308 chickens (BW: 43.52 ± 0.68 g) were randomly allotted to 4 treatments (6 replicates with 32 broilers in each): 1) basal diet (NC); 2) basal diet with 30 mg/kg of avilamycin (PC); 3) basal diet with 1,000 mg/kg of BA (PBA); and 4) basal diet with benzocal-50 (330, 330, and 300 mg/kg in the starter (d 1-14), grower (d 15–28), and finisher (d 29–41) phases) (EBA). The normal stocking density during the finisher phase for broilers is 25.0 kg BW/m², but this study used a density of 29.0 kg BW/m² for a high stocking density. The results revealed an increase in the ADG of the EBA treatment compared to the PBA treatment during d 8 to 14 (<em>P</em> < 0.05). In the grower (d 15–28) and finisher (d 29–41) phases, chickens fed the EBA treatment exhibited lower intestinal digesta pH values than those in the NC treatment (<em>P</em> < 0.05). Moreover, the EBA treatment displayed greater AID of dry matter and crude protein than the PC treatment (<em>P</em> < 0.05). The EBA treatment resulted in an upregulation of sodium-dependent neutral amino acid transporter and peptide transporter (<strong>PEPT1</strong>) mRNA expressions in the jejunum on d 14, an increased sodium-glucose transport protein 1 mRNA expression in the jejunum on d 28, and enhanced PEPT1 mRNA expression in the jejunum on d 41, when compared to the NC treatment (<em>P</em> < 0.05). Moreover, the EBA treatment improved cadherin 1 mRNA expression in the jejunum on d 28 than the NC and PC treatments (<em>P</em> < 0.05). Overall, supplementing benzocal-50 to broilers under a high stocking density led to a decrease in gut pH, contributing to reduced fecal score and an overall enhancement in the gut barrier function.</p></div>\",\"PeriodicalId\":15240,\"journal\":{\"name\":\"Journal of Applied Poultry Research\",\"volume\":\"33 3\",\"pages\":\"Article 100454\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2024-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1056617124000539/pdfft?md5=65de4873c012fbcfa3979afddbee9a8d&pid=1-s2.0-S1056617124000539-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Poultry Research\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1056617124000539\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"AGRICULTURE, DAIRY & ANIMAL SCIENCE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Poultry Research","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1056617124000539","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"AGRICULTURE, DAIRY & ANIMAL SCIENCE","Score":null,"Total":0}
Effects of benzoic acid or benzocal-50 supplementation on growth performance and intestinal health in mixed-sex Ross 308 chickens under a high stocking density
An experiment was conducted to evaluate the impacts of dietary supplementation with unprotected benzoic acid (BA) or benzocal-50 (protected BA) on the growth performance and intestinal health in mixed-sex Ross 308 broilers under a high stocking density. A total of 768 one-d-old mixed-sex Ross 308 chickens (BW: 43.52 ± 0.68 g) were randomly allotted to 4 treatments (6 replicates with 32 broilers in each): 1) basal diet (NC); 2) basal diet with 30 mg/kg of avilamycin (PC); 3) basal diet with 1,000 mg/kg of BA (PBA); and 4) basal diet with benzocal-50 (330, 330, and 300 mg/kg in the starter (d 1-14), grower (d 15–28), and finisher (d 29–41) phases) (EBA). The normal stocking density during the finisher phase for broilers is 25.0 kg BW/m², but this study used a density of 29.0 kg BW/m² for a high stocking density. The results revealed an increase in the ADG of the EBA treatment compared to the PBA treatment during d 8 to 14 (P < 0.05). In the grower (d 15–28) and finisher (d 29–41) phases, chickens fed the EBA treatment exhibited lower intestinal digesta pH values than those in the NC treatment (P < 0.05). Moreover, the EBA treatment displayed greater AID of dry matter and crude protein than the PC treatment (P < 0.05). The EBA treatment resulted in an upregulation of sodium-dependent neutral amino acid transporter and peptide transporter (PEPT1) mRNA expressions in the jejunum on d 14, an increased sodium-glucose transport protein 1 mRNA expression in the jejunum on d 28, and enhanced PEPT1 mRNA expression in the jejunum on d 41, when compared to the NC treatment (P < 0.05). Moreover, the EBA treatment improved cadherin 1 mRNA expression in the jejunum on d 28 than the NC and PC treatments (P < 0.05). Overall, supplementing benzocal-50 to broilers under a high stocking density led to a decrease in gut pH, contributing to reduced fecal score and an overall enhancement in the gut barrier function.
期刊介绍：
The Journal of Applied Poultry Research (JAPR) publishes original research reports, field reports, and reviews on breeding, hatching, health and disease, layer management, meat bird processing and products, meat bird management, microbiology, food safety, nutrition, environment, sanitation, welfare, and economics. As of January 2020, JAPR will become an Open Access journal with no subscription charges, meaning authors who publish here can make their research immediately, permanently, and freely accessible worldwide while retaining copyright to their work. Papers submitted for publication after October 1, 2019 will be published as Open Access papers.
The readers of JAPR are in education, extension, industry, and government, including research, teaching, administration, veterinary medicine, management, production, quality assurance, product development, and technical services. Nutritionists, breeder flock supervisors, production managers, microbiologists, laboratory personnel, food safety and sanitation managers, poultry processing managers, feed manufacturers, and egg producers use JAPR to keep up with current applied poultry research.
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