多系统萎缩-帕金森病型患者使用左旋多巴后交感神经皮肤反应的恢复。

IF 0.6 4区医学 Q4 CLINICAL NEUROLOGY Neurocase Pub Date : 2024-08-01 Epub Date: 2024-07-29 DOI:10.1080/13554794.2024.2381855

Halil Onder, Mustafa Yurtdas, Selcuk Comoglu

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引用次数: 0

摘要

在此，我们报告了一名 62 岁的女性多系统萎缩症（MSA）患者，在初步检查时，她的交感神经皮肤反应（SSRs）并不明显。然而，左旋多巴治疗使交感神经皮肤反应恢复正常，并适度改善了直立性低血压相关症状。基于这一罕见病例，我们讨论了 MSA 患者自主神经功能紊乱的可能病理生理学机制。我们认为今后有必要在这一领域开展临床和实验研究。

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The recovery of sympathetic skin responses with levodopa in a patient with multiple system atrophy-parkinsonian type.

Herein, we report a 62-year-old female patient with Multiple system atrophy (MSA) at whom the sympathetic skin responses (SSRs) were absent at initial investigations. However, the levodopa therapy provided normalization of SSRs and moderately improvement in orthostatic hypotension-related symptoms. Based on this rare illustration, we discuss the possible mechanisms underlying the pathophysiology of autonomic dysfunction in MSA. We remark on the need for future clinical and experimental studies in this field.

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来源期刊

Neurocase 医学-精神病学

CiteScore

1.40

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.