原发性唾液腺恶性肿瘤:术后随访时间和调查综述

Yuvarahj Pathmanathan, Vinod Prabhu, Khadija Jafari
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摘要

唾液腺癌(SGC)是一种罕见的肿瘤,具有多种组织学异质性。大多数 SGCs 患者没有症状,因为它们通常生长缓慢且局限于局部。原发性手术切除是 SGCs 的基础治疗方法,在特定病例中还会进行放射治疗。对于具体的术后标准指南,目前还没有达成共识。患者需要接受数年的随访,但目前有关这一主题的文献较少阐明商定的随访时间。远处转移是治疗失败的主要原因。术后疾病复发或远处转移的诊断证据在很大程度上取决于放射学检查。如果对 SGCs 患者实施结构合理、时间较长的随访计划,其疗效会更好。本综述旨在就 SGC 患者术后适当的随访时间和放射学检查方式提出建议。
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Primary Salivary Gland Malignancy: A Review on Post-Operative Follow-Up Duration and Investigations
Salivary gland cancers (SGC) are rare neoplasms that exhibit a wide array of histological heterogeneities. Most patients presenting with SGCs are asymptomatic, as they are typically slow-growing and localized. Primary surgical resection is the cornerstone treatment for SGCs and radiotherapy is performed in selected cases. There is no consensus on concrete standard post-operative guidelines. Patients are followed-up for years, however an agreed duration of follow-up is less elucidated in the literature present on the subject. Distant metastases are the primary cause of treatment failure. Post-operative diagnostic evidence of disease recurrence or distant metastases is heavily guided by radiological examinations. Patients with SGCs have better outcomes with a well-structured and lengthy follow-up plan. This review aims to suggest an appropriate follow-up duration and radiological modalities used post-operatively for SGC patients.
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