Muhammad Firdaus Mohd Fauzi, Nasrul Hadi Johari, Mohd Jamil Mohamed Mokhtarudin, Bazli Mohd Yusoff, Baolei Guo
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引用次数: 0
摘要
该研究介绍了外周动脉疾病(PAD)几何中的流固耦合(FSI)建模,突出了动脉阻塞对血液动力学和动脉壁力学的影响。该研究采用基于 RANS 的 SST-Tran 模型,在现实边界条件下研究了狭窄的 PAD 模型,并结合超弹性的 Mooney-Rivlin 模型模拟了动脉壁的响应。分析包括速度曲线、壁剪应力(WSS)、压力分布和壁位移,揭示了健康模型和狭窄模型之间的显著差异。它展示了适应性血液动力学、狭窄对流动力学的影响以及对动脉粥样硬化和斑块形成的潜在影响。研究结果强调了了解狭窄严重程度对于临床风险评估、治疗计划和监测的重要性。
Fluid-Structure Interaction Modelling of Blood Flow in Peripheral Arterial Disease
The study presents the fluid-structure interaction (FSI) modeling in Peripheral Arterial Disease (PAD) geometry, highlighting the effects of arterial blockage on hemodynamics and arterial wall mechanics. Employing a RANS-based SST-Tran model, the study examines stenotic PAD models under realistic boundary conditions, coupled with a hyperelastic Mooney-Rivlin model to simulate the arterial wall's response. The analysis includes velocity profiles, wall shear stress (WSS), pressure distribution, and wall displacement, revealing significant differences between healthy and stenosed models. It demonstrates adaptive hemodynamics, the impact of stenosis on flow mechanics, and potential implications for atherosclerosis and plaque formation. The findings highlight the importance of understanding stenosis severity for clinical risk assessment, treatment planning, and monitoring.
期刊介绍:
This journal welcomes high-quality original contributions on experimental, computational, and physical aspects of fluid mechanics and thermal sciences relevant to engineering or the environment, multiphase and microscale flows, microscale electronic and mechanical systems; medical and biological systems; and thermal and flow control in both the internal and external environment.