{"title":"一种新的异香豆素衍生物，来自于越橘内生真菌新孢子瘤 Pezicula neosporulosa VDB39。","authors":"Yuan-Cao Shu, Zhi-Yu Zhang, Xiao-Man Fu, Wei-Lin Zeng, Guo-Lei Zhu, Xiao-Qin Yang, Si-Da Xie, Wei-Hua Wang, Ping Zhao","doi":"10.1080/10286020.2024.2385367","DOIUrl":null,"url":null,"abstract":"<p><p>Four isocoumarin derivatives (<b>1-4</b>) and five phenols (<b>5-9</b>) were obtained from the endophytic fungus <i>Pezicula neosporulosa</i> VDB39, which was isolated from the branches of <i>Vaccinium dunalianum</i> Wight (Ericaceae). Compound <b>1</b> is a new derivative of isocoumarin. The structures were elucidated by spectroscopic methods. Single X-ray crystallography confirmed the absolute configuration of compound <b>1</b>. Additionally, the antiphytopathogenic fungi activity of isocoumarin derivatives (<b>1-4</b>) was evaluated.</p>","PeriodicalId":15180,"journal":{"name":"Journal of Asian Natural Products Research","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A new isocoumarin derivative from endophytic fungus <i>Pezicula neosporulosa</i> VDB39 from <i>Vaccinium dunalianum</i>.\",\"authors\":\"Yuan-Cao Shu, Zhi-Yu Zhang, Xiao-Man Fu, Wei-Lin Zeng, Guo-Lei Zhu, Xiao-Qin Yang, Si-Da Xie, Wei-Hua Wang, Ping Zhao\",\"doi\":\"10.1080/10286020.2024.2385367\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Four isocoumarin derivatives (<b>1-4</b>) and five phenols (<b>5-9</b>) were obtained from the endophytic fungus <i>Pezicula neosporulosa</i> VDB39, which was isolated from the branches of <i>Vaccinium dunalianum</i> Wight (Ericaceae). Compound <b>1</b> is a new derivative of isocoumarin. The structures were elucidated by spectroscopic methods. Single X-ray crystallography confirmed the absolute configuration of compound <b>1</b>. Additionally, the antiphytopathogenic fungi activity of isocoumarin derivatives (<b>1-4</b>) was evaluated.</p>\",\"PeriodicalId\":15180,\"journal\":{\"name\":\"Journal of Asian Natural Products Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Asian Natural Products Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/10286020.2024.2385367\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Asian Natural Products Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10286020.2024.2385367","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
A new isocoumarin derivative from endophytic fungus Pezicula neosporulosa VDB39 from Vaccinium dunalianum.
Four isocoumarin derivatives (1-4) and five phenols (5-9) were obtained from the endophytic fungus Pezicula neosporulosa VDB39, which was isolated from the branches of Vaccinium dunalianum Wight (Ericaceae). Compound 1 is a new derivative of isocoumarin. The structures were elucidated by spectroscopic methods. Single X-ray crystallography confirmed the absolute configuration of compound 1. Additionally, the antiphytopathogenic fungi activity of isocoumarin derivatives (1-4) was evaluated.
期刊介绍：
The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures.
All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.
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