首例免疫功能正常的患者因金黄色棒状杆菌引起的尿毒症。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-01-01 Epub Date: 2024-05-24 DOI:10.1080/17460913.2024.2344953
Lucia Corich, Carmen Losasso, Alessia Meneghel, Francesca Irene Blarasin, Giancarlo Basaglia, Maria Ada Corich
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引用次数: 0

摘要

非二白喉科里纳菌败血症非常罕见,迄今为止只有免疫力低下或特别易感的患者才会患上这种疾病。我们介绍了首例由琥珀色棒状杆菌(Corynebacterium aurimucosum)引起的尿毒症病例,患者是一名 67 岁的女性,无任何已知的免疫缺陷,也未接受任何免疫抑制治疗,因发热和急性呼吸困难入院。这项研究提出了一种新的方法来评估棒状杆菌的分离,尤其是从血液中分离出来的棒状杆菌。特别是,它强调了 C. aurimucosum(通常被认为是一种污染物,很少被确定为感染的病原体)的潜在感染作用及其临床后果,还详细介绍了其微生物学诊断和相关治疗的有趣方面,并澄清了文献中的对比数据。
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The first case of urosepsis caused by Corynebacterium aurimucosum in an immunocompetent patient.

Non-diphtheroid Corynebacterium sepsis is rare and has affected only immunocompromised or particularly predisposed patients so far. We present the first case of urosepsis caused by Corynebacterium aurimucosum in a 67-year-old woman, without any known immunodeficiencies and in absence of any immunosuppressive therapy, admitted to the hospital for fever and acute dyspnea. This work suggests a new approach in evaluating the isolation of Corynebacteria, especially if isolated from blood. In particular, it highlights the potential infectious role of C. aurimucosum (often considered a contaminant and only rarely identified as an etiological agent of infections) and its clinical consequences, detailing also interesting aspects about its microbiological diagnosis and relative therapy and clarifying contrasting data of literature.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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