混合闭环系统对 1 型糖尿病儿童和青少年体育锻炼的有效性:现实生活中的横断面研究。

Ruben Martin-Payo , Maria del Mar Fernandez-Alvarez , Rebeca García-García , Ángela Pérez-Varela , Shelini Surendran , Isolina Riaño-Galán
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引用次数: 0

摘要

研究目的研究旨在描述体育锻炼如何影响使用混合闭环系统的儿童的代谢控制、胰岛素需求和碳水化合物摄入量:横断面研究设计。样本包括 21 名确诊为 1 型糖尿病的儿童和青少年。研究期间,对参与者进行了为期 7 天的监测,以收集有关这些因素的综合数据:结果:9 名参与者(42.9%)转为运动模式,将目标血糖暂时提高到 150 毫克/分升。HbA1c 值介于 5.5% 至 7.9% 之间(中位数为 6.5%;IQR 为 0.75)。在 70-180 毫克/分升目标范围内的时间百分比相似;但是,高血糖持续时间延长,运动日的自动校正次数增多。与非运动日相比,运动日处于严重高血糖状态(>250 毫克/分升)的时间增加了 2.7%(P = 0.02)。值得注意的是,与非运动日相比,运动日的低血糖发作次数并未增加:混合闭环系统对患有 1 型糖尿病的儿童和青少年在现实生活中进行竞技运动时是有效和安全的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Effectiveness of a hybrid closed-loop system for children and adolescents with type 1 diabetes during physical exercise: A cross-sectional study in real life

Objective

The aim of the study was to describe how physical exercise affects metabolic control, insulin requirements and carbohydrate intake in children who use hybrid closed-loop systems.

Methods

Cross-sectional study design. The sample included 21 children and adolescents diagnosed with type 1 diabetes. During the study, participants were monitored for a period of 7 days to gather comprehensive data on these factors.

Results

Nine participants (42.9%) had switched to exercise mode to raise the target glucose temporarily to 150 mg/dL. The HbA1c values ranged from 5.5% to 7.9% (median, 6.5%; IQR, 0.75). The percentage of time within the target range of 70−180 mg/dL was similar; however, there was an increased duration of hyperglycaemia and more autocorrections on exercise days. The time spent in severe hyperglycaemia (>250 mg/dL) increased by 2.7% in exercise compared to non-exercise days (P = .02). It is worth noting that hypoglycaemic episodes did not increase during the exercise days compared with non-exercise days.

Conclusion

The hybrid closed-loop system was effective and safe in children and adolescents with type 1 diabetes during the performance of competitive sports in real life.

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