肉样瘤病:概述

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS ACS Applied Bio Materials Pub Date : 2024-08-12 DOI:10.1186/s42358-024-00381-z
Fabricio Souza Neves, Ivanio Alves Pereira, Flavio Sztajnbok, Nilton Salles Rosa Neto
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引用次数: 0

摘要

肉样瘤病是一种原因不明的全身性炎症性疾病,由多个无菌非酪氨酸肉芽肿形成。考虑到几乎所有患者都会出现肺部或纵隔淋巴结病变,吸入抗原被认为是易感人群发病的诱因。肺外表现既常见又多样:几乎任何器官系统都可能受到影响,治疗方法也从简单的观察等待到强烈的免疫抑制不等。本文将综述当前有关肉样瘤病的概念,重点介绍其主要临床表型的识别和治疗。
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Sarcoidosis: a general overview
Sarcoidosis is a systemic inflammatory disease of unknown origin, which consists of the formation of multiple sterile noncaseating granulomas. Inhaled antigens are believed to initiate disease in prone individuals, considering that almost all patients present pulmonary or mediastinal lymph node disease. Extrapulmonary manifestations are common and diverse: practically any organ system can be affected, and treatment can range from simple watchful waiting to intense immunosuppression. In this article, we review current concepts about sarcoidosis in an overview, focusing on recognition and treatment of its major clinical phenotypes.
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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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