弧菌引起的败血症:不可掉以轻心的热带传染病。

C H Ding, W A Wahab, M S Saaid, M N Mokhtar, F A Abdullah, I Azaharuddin
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引用次数: 0

摘要

弧菌是一种嗜卤革兰阴性杆菌,可在免疫力低下的患者中引起暴发性败血症。一名 67 岁的男子因接受细胞毒性化疗而导致免疫抑制,病史简短,表现为发热、嗜睡、肌痛和口服量减少。他最近曾去海边吃海鲜。他的血压为 81/47 mm Hg,需要进行液体复苏和肌力支持,并被送入重症监护室。他的血液培养呈弯曲革兰氏阴性杆菌阳性。分离出的菌株氧化酶阳性,在三糖铁琼脂中产生带碱性斜面的酸性对接。基质辅助激光解吸电离飞行时间质谱法最终确定该分离菌为弧菌。静脉注射头孢他啶加环丙沙星,入院第五天,他被成功转到普通病房。患者总共完成了 14 天的抗生素治疗。
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Septicaemia due to Vibrio vulnificus: A tropical infection not to be taken lightly.

Vibrio vulnificus is a halophilic gram-negative bacillus that can cause fulminant septicaemia in immunocompromised patients. A 67-year-old man who was immunosuppressed as a result of cytotoxic chemotherapy presented with a brief history of fever, lethargy, myalgia, and reduced oral intake. He had recently travelled to the beach to consume seafood. His blood pressure was 81/47 mm Hg, necessitating fluid resuscitation followed by inotropic support and admission to the intensive care unit. His blood culture was positive for curved gram-negative bacilli. The isolate was oxidase-positive and produced an acid butt with an alkaline slant in triple sugar iron agar. Matrix-assisted laser desorption ionization-time of flight mass spectrometry conclusively identified the isolate as V. vulnificus. Intravenous ceftazidime plus ciprofloxacin were administered, and by the fifth day of admission, he was successfully transferred out to the general ward. In total, the patient completed a 14-day course of antibiotic therapy.

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