起源于房间隔的原发性心脏滑膜肉瘤及相关肺梗塞：一份病例报告。

IF 2.7 3区医学 Q3 ONCOLOGY Journal of Cancer Research and Clinical Oncology Pub Date : 2024-08-20 DOI:10.1007/s00432-024-05852-w

Nie Xu, Kang Xie, Dong Xin, Zhonglei Liang, Yongjun Zeng

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摘要

背景：原发性心脏滑膜肉瘤是一种罕见疾病，晚期患者的治疗方案有限。手术和化疗是目前的主要治疗方法，但存活率仍然很低：一名 64 岁的妇女出现胸闷和气短症状，被发现患有阻塞性右心房肿块，并伴有肺梗塞和转移。她最终被诊断为晚期原发性心脏滑膜肉瘤。手术后，患者的症状有所改善，并接受了化疗和抗血管生成治疗，但遗憾的是，她的存活时间只有 8 个月：本病例报告旨在加深临床医生对原发性心脏滑膜肉瘤诊断和治疗的理解。提高原发性心脏滑膜肉瘤患者的生存率和生活质量仍是一项重大挑战。

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Primary cardiac synovial sarcoma originating from the atrial septum and associated pulmonary infarction: a case report.

Background: Primary cardiac synovial sarcoma is a rare condition with limited treatment options for advanced stages. Surgery and chemotherapy are currently the mainstay treatments; however, survival rates remain low.

Case presentation: A 64-year-old woman presenting with symptoms of chest tightness and shortness of breath was found to have an obstructive right atrial mass, along with pulmonary infarction and metastasis. She was ultimately diagnosed with advanced primary cardiac synovial sarcoma. Following surgery, the patient's symptoms improved, and she underwent chemotherapy and anti-angiogenic therapy, but unfortunately, her survival time was only 8 months.

Conclusion: This case report aims to enhance clinicians' understanding of the diagnosis and treatment of primary cardiac synovial sarcoma. Enhancing both survival outcomes and quality of life in individuals with primary cardiac synovial sarcoma continues to present a significant challenge.

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来源期刊

Journal of Cancer Research and Clinical Oncology 医学-肿瘤学

CiteScore

4.00

自引率

2.80%

发文量

577

审稿时长

2 months

期刊介绍： The "Journal of Cancer Research and Clinical Oncology" publishes significant and up-to-date articles within the fields of experimental and clinical oncology. The journal, which is chiefly devoted to Original papers, also includes Reviews as well as Editorials and Guest editorials on current, controversial topics. The section Letters to the editors provides a forum for a rapid exchange of comments and information concerning previously published papers and topics of current interest. Meeting reports provide current information on the latest results presented at important congresses. The following fields are covered: carcinogenesis - etiology, mechanisms; molecular biology; recent developments in tumor therapy; general diagnosis; laboratory diagnosis; diagnostic and experimental pathology; oncologic surgery; and epidemiology.