Antonio Frontera MD, PhD, Andrea Mazzanti MD, PhD, Bernard Belhassen MD, Silvia Priori MD, PhD
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Induction of ventricular fibrillation during programmed ventricular stimulation in a patient with CASQ2 heterozygous mutation
Introduction
We report the case of a 37-year-old male athlete, who developed during exercise atrial and ventricular arrhythmias. No structural heart disease.
Results
Invasive programmed ventricular stimulation induced ventricular fibrillation. A heterozygous mutation in the CASQ2 gene (c.775G>T, p.E259X) was found.
Conclusions
The findings in our patient may suggest some increased ventricular excitability using programmed ventricular stimulation in CASQ2 polymorphic ventricular tachycardia patients.
期刊介绍:
Journal of Cardiovascular Electrophysiology (JCE) keeps its readership well informed of the latest developments in the study and management of arrhythmic disorders. Edited by Bradley P. Knight, M.D., and a distinguished international editorial board, JCE is the leading journal devoted to the study of the electrophysiology of the heart.