外源性精神病卷土重来:对药物诱发精神病理学的现象学研究。

IF 1.6 4区 医学 Q3 CLINICAL NEUROLOGY Journal of Nervous and Mental Disease Pub Date : 2024-09-01 DOI:10.1097/NMD.0000000000001800
Valerio Ricci, Giuseppe Maina, Gilberto Di Petta, Giovanni Martinotti
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引用次数: 0

摘要

摘要:与药物使用相关的精神病理学表现,包括诱发精神病的经历,越来越受到医学界的关注,但却没有得到很好的理解。大麻和可卡因等新型精神活性物质和旧化合物的增效作用已成为全球关注的问题,尤其是在青少年和年轻成年人中。从药物诱发的精神病(SIP)到持续性精神病的转变率很高,尤其是在大麻诱发的精神病中。对诱发精神病现象的科学研究揭示了 SIP 与原发性精神病之间的差异,并强调了与两者相关的风险因素。外源性精神病的概念,包括被称为麦角酰精神瘤的毒性变体,为了解外部因素在精神病发展中的作用提供了宝贵的见解。现象学方法将这种感知中断描述为时空维度的转移,导致听觉和视觉幻觉。意识的 "黄昏状态 "在从药物使用到精神病的转变过程中起着至关重要的作用,对空间性、主体间性和时间性都有影响。通往精神病的这一复杂路径挑战了传统的诊断模型,强调了对药物诱发的精神病理体验进行更细致入微的理解的必要性。
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The Resurgence of Exogenous Psychosis: A Phenomenological Examination of Substance-Induced Psychopathology.

Abstract: The psychopathological manifestations associated with substance use, including induced psychotic experiences, are increasingly relevant but not well-understood within the medical community. Novel psychoactive substances and potentiated old compounds like cannabis and cocaine have emerged as a global concern, especially among adolescents and young adults. Transition rates from substance-induced psychosis (SIP) to persistent psychosis are significant, particularly in cases of cannabis-induced psychosis. Scientific inquiry into induced psychotic phenomena has revealed differences between SIP and primary psychotic disorders, highlighting the risk factors associated with each. The concept of exogenous psychosis, including its toxic variant known as lysergic psychoma, provides valuable insights into the role of external factors in psychosis development. A phenomenological approach characterizes this disruption in perception as a shift in temporal and spatial dimensions, leading to auditory and visual hallucinations. The "twilight state" of consciousness plays a crucial role in the transition from substance use to psychosis, with implications for spatiality, intersubjectivity, and temporality. This complex path to psychosis challenges traditional diagnostic models and underscores the need for a more nuanced understanding of substance-induced psychopathological experiences.

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来源期刊
CiteScore
2.90
自引率
5.30%
发文量
233
审稿时长
3-8 weeks
期刊介绍: The Journal of Nervous and Mental Disease publishes peer-reviewed articles containing new data or ways of reorganizing established knowledge relevant to understanding and modifying human behavior, especially that defined as impaired or diseased, and the context, applications and effects of that knowledge. Our policy is summarized by the slogan, "Behavioral science for clinical practice." We consider articles that include at least one behavioral variable, clear definition of study populations, and replicable research designs. Authors should use the active voice and first person whenever possible.
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