{"title":"超越苍白:对色素沉着性真菌病的认识--一份病例报告。","authors":"Zauddin Nur Zafirah, Azwanis Abdul Hadi","doi":"10.51866/cr.644","DOIUrl":null,"url":null,"abstract":"<p><p>Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma, a type of extranodal non-Hodgkin lymphoma. This report presents the case of a 9-year-old boy with a 2-year history of asymptomatic, hypopigmented skin lesions that were resistant to topical treatment. He was initially treated for a fungal skin infection and had received multiple courses of topical antifungals and steroids but showed no improvement, which led to further evaluation and a referral to a dermatologist. A skin biopsy was performed, and the diagnosis of hypopigmented MF was confirmed through skin histopathology and immunohistochemistry study. His lesions responded well to cycles of narrowband ultraviolet B phototherapy, showing almost complete clearance after 4 months without any side effects.</p>","PeriodicalId":40017,"journal":{"name":"Malaysian Family Physician","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366274/pdf/","citationCount":"0","resultStr":"{\"title\":\"Beyond the pale: Insights into hypopigmented mycosis fungoides - A case report.\",\"authors\":\"Zauddin Nur Zafirah, Azwanis Abdul Hadi\",\"doi\":\"10.51866/cr.644\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma, a type of extranodal non-Hodgkin lymphoma. This report presents the case of a 9-year-old boy with a 2-year history of asymptomatic, hypopigmented skin lesions that were resistant to topical treatment. He was initially treated for a fungal skin infection and had received multiple courses of topical antifungals and steroids but showed no improvement, which led to further evaluation and a referral to a dermatologist. A skin biopsy was performed, and the diagnosis of hypopigmented MF was confirmed through skin histopathology and immunohistochemistry study. His lesions responded well to cycles of narrowband ultraviolet B phototherapy, showing almost complete clearance after 4 months without any side effects.</p>\",\"PeriodicalId\":40017,\"journal\":{\"name\":\"Malaysian Family Physician\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-08-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366274/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Malaysian Family Physician\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.51866/cr.644\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Nursing\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malaysian Family Physician","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51866/cr.644","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Nursing","Score":null,"Total":0}
引用次数: 0
摘要
色素沉着性真菌病(MF)是皮肤T细胞淋巴瘤的一种罕见变异型,是一种结节外非霍奇金淋巴瘤。本报告所介绍的病例是一名 9 岁男孩,他的无症状、色素减退性皮肤病变已有 2 年病史,且对局部治疗产生耐药性。他最初因皮肤真菌感染接受了治疗,并接受了多个疗程的局部抗真菌药物和类固醇药物治疗,但病情未见好转,因此需要进一步评估并转诊至皮肤科医生。医生对他进行了皮肤活检,并通过皮肤组织病理学和免疫组化研究确诊为色素减退性中耳炎。他的皮损对窄带紫外线 B 光疗反应良好,4 个月后几乎完全消退,且无任何副作用。
Beyond the pale: Insights into hypopigmented mycosis fungoides - A case report.
Hypopigmented mycosis fungoides (MF) is a rare variant of cutaneous T-cell lymphoma, a type of extranodal non-Hodgkin lymphoma. This report presents the case of a 9-year-old boy with a 2-year history of asymptomatic, hypopigmented skin lesions that were resistant to topical treatment. He was initially treated for a fungal skin infection and had received multiple courses of topical antifungals and steroids but showed no improvement, which led to further evaluation and a referral to a dermatologist. A skin biopsy was performed, and the diagnosis of hypopigmented MF was confirmed through skin histopathology and immunohistochemistry study. His lesions responded well to cycles of narrowband ultraviolet B phototherapy, showing almost complete clearance after 4 months without any side effects.
期刊介绍:
The Malaysian Family Physician is the official journal of the Academy of Family Physicians of Malaysia. It is published three times a year. Circulation: The journal is distributed free of charge to all members of the Academy of Family Physicians of Malaysia. Complimentary copies are also sent to other organizations that are members of the World Organization of Family Doctors (WONCA).