{"title":"变异链球菌对混合菌种生物膜中白色念珠菌生长的积极影响及其对牙齿健康的意义。","authors":"X Wang, S F Yap, Y F Ngeow","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Candida albicans and Streptococcus mutans co-exist in biofilms in the oral cavity. In this study, the impact of S. mutans on the growth of C. albicans within a mixed-species biofilm was examined.</p><p><strong>Materials and methods: </strong>Single species C. albicans biofilms and mixed species biofilms containing C. albicans and S. mutans at 1:3 and 1:10 ratios were constructed in 6-well microtiter plates. After 24 hours of incubation, the density of resuspended biofilm cells was determined as CFU/ml and used to compare the growth of C. albicans in single species and mixed species biofilms.</p><p><strong>Results: </strong>The CFU/ml of C. albicans in mixed-species biofilms was found to be higher than that in single-species biofilms.</p><p><strong>Conclusion: </strong>S. mutans promotes the growth of C. albicans in a co-inhabited biofilm.</p>","PeriodicalId":48723,"journal":{"name":"Malaysian Journal of Pathology","volume":"46 2","pages":"295-298"},"PeriodicalIF":0.6000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The positive impact of Streptococcus mutans on the growth of Candida albicans within mixed-species biofilms and implications to dental health.\",\"authors\":\"X Wang, S F Yap, Y F Ngeow\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Candida albicans and Streptococcus mutans co-exist in biofilms in the oral cavity. In this study, the impact of S. mutans on the growth of C. albicans within a mixed-species biofilm was examined.</p><p><strong>Materials and methods: </strong>Single species C. albicans biofilms and mixed species biofilms containing C. albicans and S. mutans at 1:3 and 1:10 ratios were constructed in 6-well microtiter plates. After 24 hours of incubation, the density of resuspended biofilm cells was determined as CFU/ml and used to compare the growth of C. albicans in single species and mixed species biofilms.</p><p><strong>Results: </strong>The CFU/ml of C. albicans in mixed-species biofilms was found to be higher than that in single-species biofilms.</p><p><strong>Conclusion: </strong>S. mutans promotes the growth of C. albicans in a co-inhabited biofilm.</p>\",\"PeriodicalId\":48723,\"journal\":{\"name\":\"Malaysian Journal of Pathology\",\"volume\":\"46 2\",\"pages\":\"295-298\"},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Malaysian Journal of Pathology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PATHOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Malaysian Journal of Pathology","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PATHOLOGY","Score":null,"Total":0}
The positive impact of Streptococcus mutans on the growth of Candida albicans within mixed-species biofilms and implications to dental health.
Introduction: Candida albicans and Streptococcus mutans co-exist in biofilms in the oral cavity. In this study, the impact of S. mutans on the growth of C. albicans within a mixed-species biofilm was examined.
Materials and methods: Single species C. albicans biofilms and mixed species biofilms containing C. albicans and S. mutans at 1:3 and 1:10 ratios were constructed in 6-well microtiter plates. After 24 hours of incubation, the density of resuspended biofilm cells was determined as CFU/ml and used to compare the growth of C. albicans in single species and mixed species biofilms.
Results: The CFU/ml of C. albicans in mixed-species biofilms was found to be higher than that in single-species biofilms.
Conclusion: S. mutans promotes the growth of C. albicans in a co-inhabited biofilm.
期刊介绍：
The Malaysian Journal of Pathology is the official journal of the College of Pathologists, Academy of Medicine Malaysia. The primary purpose of The Journal is to publish the results of study and research in Pathology, especially those that have particular relevance to human disease occurring in Malaysia and other countries in this region. The term PATHOLOGY will be interpreted in its broadest sense to include Chemical Pathology, Cytology, Experimental Pathology, Forensic Pathology, Haematology, Histopathology, Immunology, Medical Microbiology and Parasitology. The Journal aims to bring under one cover publications of regional interest embracing the various sub-specialities of Pathology. It is expected that the articles published would be of value not only to pathologists, but also to medical practitioners in search of a scientific basis for the problems encountered in their practice, and to those with an interest in diseases which occur in the tropics.
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