为骨肿瘤患者设计的短弯柄非骨水泥股骨远端假体的存活率、并发症和功能效果。

IF 4.9 1区 医学 Q1 ORTHOPEDICS Bone & Joint Journal Pub Date : 2024-09-01 DOI:10.1302/0301-620X.106B9.BJJ-2024-0109.R1
Taojun Gong, Minxun Lu, Hongtao Sheng, Zhuangzhuang Li, Yong Zhou, Yi Luo, Li Min, Chongqi Tu
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引用次数: 0

摘要

目的:股骨远端肿瘤切除术后的假体内重建已被广泛提倡。在本文中,我们介绍了一种非骨水泥假体系统的设计方案,该假体系统采用短而弯曲的假体柄,旨在提高长期存活率和功能效果:本研究涉及2014年至2019年期间接受非骨水泥股骨远端假体植入术的患者,假体柄短而弯曲。我们使用 1993 年版肌肉骨骼肿瘤协会(MSTS-93)评分来评估功能结果。此外,我们还对五种并发症进行了量化,并从放射学角度评估了骨结合情况。内假体的存活率根据两个终点进行评估。研究共纳入了 134 名患者,中位年龄为 26 岁(IQR 16 至 41)。随访时间中位数为 61 个月(IQR 56 至 76),术后 MSTS-93 功能中位数为 83%(IQR 73 至 91):共有21名患者(16%)出现并发症,无菌性松动率为7%(9/134)。以无菌性松动为终点的8.5年生存率为93%,以任何原因为终点的8.5年生存率为88%:结论:使用非骨水泥股骨远端假体和短而弯曲的假体柄,无菌性松动的发生率很低,长期存活率可达9年。同时,无菌性松动通常发生在术后早期。
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Survivorship, complications, and functional outcomes of uncemented distal femoral endoprosthesis with short, curved stem for patients with bone tumours.

Aims: Endoprosthetic reconstruction following distal femur tumour resection has been widely advocated. In this paper, we present the design of an uncemented endoprosthesis system featuring a short, curved stem, with the goal of enhancing long-term survivorship and functional outcomes.

Methods: This study involved patients who underwent implantation of an uncemented distal femoral endoprosthesis with a short and curved stem between 2014 and 2019. Functional outcomes were assessed using the 1993 version of the Musculoskeletal Tumour Society (MSTS-93) score. Additionally, we quantified five types of complications and assessed osseointegration radiologically. The survivorship of the endoprosthesis was evaluated according to two endpoints. A total of 134 patients with a median age of 26 years (IQR 16 to 41) were included in our study. The median follow-up time was 61 months (IQR 56 to 76), and the median functional MSTS-93 was 83% (IQR 73 to 91) postoperatively.

Results: Overall, 21 patients (16%) encountered complications, and the rate of aseptic loosening was 7% (9/134). The survival rate up to 8.5 years was 93% for aseptic loosening as the endpoint, and 88% for any reason as the endpoint, retrospectively.

Conclusion: The use of an uncemented distal femoral endoprosthesis with a short, curved stem demonstrated a low incidence of aseptic loosening and achieved long-term survivorship of up to nine years. Meanwhile, aseptic loosening typically occurs in the early stage postoperatively.

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来源期刊
Bone & Joint Journal
Bone & Joint Journal ORTHOPEDICS-SURGERY
CiteScore
9.40
自引率
10.90%
发文量
318
期刊介绍: We welcome original articles from any part of the world. The papers are assessed by members of the Editorial Board and our international panel of expert reviewers, then either accepted for publication or rejected by the Editor. We receive over 2000 submissions each year and accept about 250 for publication, many after revisions recommended by the reviewers, editors or statistical advisers. A decision usually takes between six and eight weeks. Each paper is assessed by two reviewers with a special interest in the subject covered by the paper, and also by members of the editorial team. Controversial papers will be discussed at a full meeting of the Editorial Board. Publication is between four and six months after acceptance.
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