接受 Tedizolid 和同时服用血清素能药物的患者中血清素综合征的发生率。

IF 4.1 2区医学 Q2 MICROBIOLOGY Antimicrobial Agents and Chemotherapy Pub Date : 2024-10-08 Epub Date: 2024-09-05 DOI:10.1128/aac.00870-24

Yingsi Fang, Lloyd G Clarke, Brandon J Smith, Sunish Shah

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引用次数: 0

摘要

本研究调查了接受泰迪唑胺治疗并同时服用血清素能药物的患者中血清素综合征的实际发病率。在2015年1月至2023年7月期间，对479名成年患者进行了回顾性队列评估。总体而言，发现泰迪唑胺可能引发血清素综合征的罕见率为0.4%（2/479）。鉴于同时使用血清素能药物的情况很普遍，因此需要进一步研究以确定其因果关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Incidence of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents.

This study investigated the real-world incidence rate of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents. A retrospective cohort of 479 adult patients was assessed between January 2015 and July 2023. Overall, a rare rate of 0.4% (2/479) of possible serotonin syndrome with tedizolid was identified. Given that concomitant serotonergic agents were commonly used, further study is warranted to determine causality.

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来源期刊

Antimicrobial Agents and Chemotherapy 医学-微生物学

CiteScore

10.00

自引率

8.20%

发文量

762

审稿时长

3 months

期刊介绍： Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.