在临床法医案例中检测药物使用情况:对受害者和施暴者的尿液分析。

IF 1.5 4区 医学 Q2 MEDICINE, LEGAL Forensic Science, Medicine and Pathology Pub Date : 2024-09-05 DOI:10.1007/s12024-024-00873-w
Pia Johansson Heinsvig, Katinka Rønnow Holler, Christian Lindholst, Trine Skov Nielsen
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引用次数: 0

摘要

本研究调查了临床法医案件中受害者和施暴者使用药物的普遍程度。研究人员使用两种基于 LC-MS 的分析方法和一种 HS-GC-FID 方法,对 2019 年收集的 455 名 18 岁及以上人员的尿液样本进行了分析,以检测最常报告的滥用药物和药物治疗情况。数据库中记录了来自病例文件的数据,包括性别、年龄和个人角色。尿样和病例文件中的信息均完全匿名。最常检测到的物质是酒精(占所有案例的 37%),其次是大麻(占所有案例的 22%)和中枢神经兴奋剂(占所有案例的 24%)。检测出的其他类药物包括苯二氮卓、合成代谢类固醇、抗精神病药和抗抑郁药。在 32% 的受害者和 19% 的施暴者身上没有检测到毒品或酒精。研究还探讨了受害者和施暴者之间药物模式的相互关系,结果表明双方在事件发生时都受到了药物的影响。此外,钝器和锐器案件中的施暴者与性侵犯案件中的施暴者在使用药物方面存在显著差异。在临床法医案件中,及时采集样本并对同一案件中的受害者和施害者进行结构化毒理学分析,对于加深理解犯罪活动与药物使用之间的联系至关重要。有了这种认识,就能在知情的基础上制定预防战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Detection of substance use in clinical forensic cases: urine analysis of victims and perpetrators.

This study investigates the prevalence of substance use among victims and perpetrators involved in clinical forensic cases. Urine samples from 455 individuals aged 18 and above, collected in 2019, were analyzed using two LC-MS-based analytical methods and an HS-GC-FID method for the most frequently reported substances of abuse and medication. Data from case documents, encompassing gender, age, and the individual's role, were recorded in a database. Both the urine samples and the information from case documents were fully anonymized. The most frequently detected substance was alcohol (37% of all cases), followed by cannabis (22% of all cases) and central nervous system stimulants (24% of all cases). Other classes of substances detected included benzodiazepines, anabolic steroids, antipsychotic agents, and antidepressants. No drugs or alcohol were detected in 32% of the victims and 19% of the perpetrators. The study also examines the interrelationship of drug patterns between victims and perpetrators, and results show that both parties were influenced by substances at the time of the incident. Furthermore, there was a significant difference in the use of substances between perpetrators of blunt and sharp force cases and perpetrators in cases of sexual assault. Timely sample collection and a structured toxicological analysis of both victims and perpetrators in the same case are vital in clinical forensic cases to enhance comprehension of the connection between criminal activities and substance use. This understanding enables the development of prevention strategies at an informed level.

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来源期刊
Forensic Science, Medicine and Pathology
Forensic Science, Medicine and Pathology MEDICINE, LEGAL-PATHOLOGY
CiteScore
3.90
自引率
5.60%
发文量
114
审稿时长
6-12 weeks
期刊介绍: Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.
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