抗CRISPR解构细菌防御系统

IF 14.5 1区 生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY Molecular Cell Pub Date : 2024-09-05 DOI:10.1016/j.molcel.2024.08.008
Nils Birkholz, Peter C. Fineran
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引用次数: 0

摘要

部署抗 CRISPR 蛋白是噬菌体用来抑制细菌 CRISPR-Cas 防御的一种有效策略。在新发表的《自然》(Nature)论文中,特罗斯特等人1 发现并描述了一种令人兴奋的反CRISPR机制,其影响可能超出这场微观军备竞赛。
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Anti-CRISPRs deconstruct bacterial defense

Deploying anti-CRISPR proteins is a potent strategy used by phages to inhibit bacterial CRISPR-Cas defense. In a new Nature paper, Trost et al.1 discover and characterize an exciting anti-CRISPR mechanism with possible implications beyond this microscopic arms race.

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来源期刊
Molecular Cell
Molecular Cell 生物-生化与分子生物学
CiteScore
26.00
自引率
3.80%
发文量
389
审稿时长
1 months
期刊介绍: Molecular Cell is a companion to Cell, the leading journal of biology and the highest-impact journal in the world. Launched in December 1997 and published monthly. Molecular Cell is dedicated to publishing cutting-edge research in molecular biology, focusing on fundamental cellular processes. The journal encompasses a wide range of topics, including DNA replication, recombination, and repair; Chromatin biology and genome organization; Transcription; RNA processing and decay; Non-coding RNA function; Translation; Protein folding, modification, and quality control; Signal transduction pathways; Cell cycle and checkpoints; Cell death; Autophagy; Metabolism.
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