核磁共振成像评估整个成人生命周期的脑白质微血管血流动力学状况

IF 3.3 2区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Magnetic Resonance Imaging Pub Date : 2024-09-09 DOI:10.1002/jmri.29606

Nikou L. Damestani PhD, John Jacoby BS, Christa B. Michel BS, Barnaly Rashid PhD, David H. Salat PhD, Meher R. Juttukonda PhD

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摘要

年龄对(a) cbf、(b) att 和(d) fa 的影响，其中(c) 显示了 cbf 和 att 地图与年龄的叠加关系。结果经多重比较校正（PTFCE <0.05）和性别控制后显示。与 CBF 相比，AT 与年龄的关联更为普遍。在 PFWE < 0.05 条件下，CBF 随年龄减小与 ATT 随年龄增大之间的微分系数 = 0.8045，表明这些健康指标之间存在高度重叠。一般来说，年龄越大，FA 越低，但在内囊周围的后关节部位，年龄越大，FA 越高。Damestani 等人（1549-1562 年(1549-1562)

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MRI Assessment of Cerebral White Matter Microvascular Hemodynamics Across the Adult Lifespan

EFFECT OF AGE ON (A) CBF, (B) ATT, AND (D) FA, WHERE (C) DEMONSTRATES THE OVERLAY OF THE CBF AND ATT MAPS FOR ASSOCIATIONS WITH AGE. RESULTS ARE PRESENTED AFTER MULTIPLE COMPARISONS CORRECTION (PTFCE < 0.05) AND CONTROLLING FOR SEX. MORE WIDESPREAD ASSOCIATIONS WITH AGE ARE PREVALENT FOR ATT IN COMPARISON WITH CBF. DICE COEFFICIENT BETWEEN CBF DECREASING WITH AGE AND ATT INCREASING WITH AGE UPON THRESHOLDING AT PFWE < 0.05 = 0.8045, INDICATING HIGH OVERLAP OF THESE MEASURES OF HEMODYNAMICS. LOWER FA WAS GENERALLY ASSOCIATED WITH INCREASING AGE, THOUGH HIGHER FA WAS ASSOCIATED WITH INCREASING AGE IN THE SURROUNDING RETROLENTICULAR PART OF THE INTERNAL CAPSULE. BY DAMESTANI ET AL. (1549–1562)

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来源期刊

Journal of Magnetic Resonance Imaging 医学-核医学

CiteScore

9.70

自引率

6.80%

发文量

494

审稿时长

2 months

期刊介绍： The Journal of Magnetic Resonance Imaging (JMRI) is an international journal devoted to the timely publication of basic and clinical research, educational and review articles, and other information related to the diagnostic applications of magnetic resonance.