动脉粥样硬化免疫学：控制动脉粥样硬化的免疫系统

IF 41.7 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS Nature Reviews Cardiology Pub Date : 2024-09-11 DOI:10.1038/s41569-024-01075-1

Claudia Monaco, Lea Dib

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引用次数: 0

摘要

免疫反应就像一盘棋，白棋和黑棋扮演着对立的角色，分别策划着先天免疫、适应性免疫和解决的开局、中局和残局。经过数十年的研究，动脉免疫学研究为临床带来了第一批治疗药物。我们能否让动脉粥样硬化中的免疫系统重新同步，拯救国王？

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Atheroimmunology: keeping the immune system in atherosclerosis in check

The immune response is not unlike a game of chess, with white and black pieces playing opposing roles and orchestrating an opening, a middle and an endgame of innate immunity, adaptive immunity and resolution, respectively. After decades of research, the study of atheroimmunology has brought the first therapeutics to the clinic. Can we resynchronize the immune system in atherosclerosis and save the king?

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来源期刊

Nature Reviews Cardiology 医学-心血管系统

CiteScore

53.10

自引率

0.60%

发文量

143

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cardiology aims to be the go-to source for reviews and commentaries in the scientific and clinical communities it serves. Focused on providing authoritative and accessible articles enriched with clear figures and tables, the journal strives to offer unparalleled service to authors, referees, and readers, maximizing the usefulness and impact of each publication. It covers a broad range of content types, including Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives, catering to practising cardiologists and cardiovascular research scientists. Authored by renowned clinicians, academics, and researchers, the content targets readers in the biological and medical sciences, ensuring accessibility across various disciplines. In-depth Reviews offer up-to-date information, while Consensus Statements provide evidence-based recommendations. Perspectives and News & Views present topical discussions and opinions, and the Research Highlights section filters primary research from cardiovascular and general medical journals. As part of the Nature Reviews portfolio, Nature Reviews Cardiology maintains high standards and a wide reach.