艾曲波帕治疗伴有严重血小板减少的慢性粒细胞白血病。法语骨髓增生症小组(GFM)研究

IF 12.8 1区 医学 Q1 HEMATOLOGY Leukemia Pub Date : 2024-09-12 DOI:10.1038/s41375-024-02402-8
Florence Rabian, Sylvie Chevret, Bérengère Gruson, Sylvain Thépot, Anouk Walter-Petrich, Thorsten Braun, Norbert Vey, José Miguel Torregrosa-Diaz, Pierre Peterlin, Andrea Toma, Maud D’Aveni, Jacques Delaunay, Laurence Legros, Nathalie Droin, Fatiha Chermat, Daniel Lusina, Lionel Adès, Rosa Sapena, Eric Solary, Pierre Fenaux, Raphael Itzykson
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引用次数: 0

摘要

10%-30%的慢性粒细胞白血病(CMML)会出现严重血小板减少症(50 ×109/L),并因出血和疾病进展风险增加而导致大量死亡[1]。血小板生成素受体激动剂 Eltrombopag 可改善低危骨髓增生异常综合征患者的血小板计数[3]。在多达 11 例患者的回顾性病例系列中[4,5,6],或作为 MDS I 期试验的一部分[7],研究了 Eltrombopag 对 CMML 的活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Eltrombopag in chronic myelomonocytic leukemia with severe thrombocytopenia. A Groupe Francophone des Myélodysplasies (GFM) study
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来源期刊
Leukemia
Leukemia 医学-血液学
CiteScore
18.10
自引率
3.50%
发文量
270
审稿时长
3-6 weeks
期刊介绍: Title: Leukemia Journal Overview: Publishes high-quality, peer-reviewed research Covers all aspects of research and treatment of leukemia and allied diseases Includes studies of normal hemopoiesis due to comparative relevance Topics of Interest: Oncogenes Growth factors Stem cells Leukemia genomics Cell cycle Signal transduction Molecular targets for therapy And more Content Types: Original research articles Reviews Letters Correspondence Comments elaborating on significant advances and covering topical issues
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