紫外线激光脉冲持续时间和波长对成纤维细胞影响的研究

IF 0.4 Q4 PHYSICS, PARTICLES & FIELDS Physics of Particles and Nuclei Letters Pub Date : 2024-08-14 DOI:10.1134/s1547477124700717
Y. M. Hamdan, D. A. Makarova, N. I. Shamsutdinov, P. V. Zelenikhin, A. S. Nizamutdinov, A. A. Buglak, T. A. Telegina
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引用次数: 0

摘要

摘要 我们报告了锂(Lu,Y)F4:Ce 激光的 UVB 辐射脉冲持续时间和波长对人类皮肤成纤维细胞的细胞毒性效应。照射 24 小时后进行 MTT 试验,观察到活力参数上升。流式细胞仪显示,80.8 ± 6.9% 的细胞膜受损,只有 6.2 ± 2.2% 的细胞达到晚期凋亡阶段,因此它们有可能恢复细胞质膜并随后分裂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Study of the Effect of UV Laser Pulse Duration and Wavelength on Fibroblasts

Abstract

We report the cytotoxic effect of pulse duration and wavelength of UVB laser radiation from Li(Lu,Y)F4:Ce laser on human skin fibroblasts. When performing the MTT test 24 h after irradiation, an increase in the viability parameter was observed. Flow cytometry showed that 80.8 ± 6.9% of cells have a damaged membrane and only 6.2 ± 2.2% reach the stage of late apoptosis, due to which they have the potential to restore the cytoplasmic membrane and subsequently divide.

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来源期刊
Physics of Particles and Nuclei Letters
Physics of Particles and Nuclei Letters PHYSICS, PARTICLES & FIELDS-
CiteScore
0.80
自引率
20.00%
发文量
108
期刊介绍: The journal Physics of Particles and Nuclei Letters, brief name Particles and Nuclei Letters, publishes the articles with results of the original theoretical, experimental, scientific-technical, methodological and applied research. Subject matter of articles covers: theoretical physics, elementary particle physics, relativistic nuclear physics, nuclear physics and related problems in other branches of physics, neutron physics, condensed matter physics, physics and engineering at low temperatures, physics and engineering of accelerators, physical experimental instruments and methods, physical computation experiments, applied research in these branches of physics and radiology, ecology and nuclear medicine.
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