镍钛合金在血管介入医疗器械中的应用和进展

Minghao Yin, Tianju Chen, Ping Liu, Xun Ma, Shirui Zhou, Li Shen, Shuangyuan Wang, Wei Li
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引用次数: 0

摘要

如今,全球每年因心脑血管疾病导致的死亡率大幅攀升,而用于介入治疗的传统不锈钢材料有时并不适合较薄的血管壁。因此,对血管介入领域的新型材料进行全面分析势在必行,而镍钛合金是其中最好的材料之一。镍钛合金是形状记忆合金,在一定温度和压力下会发生相变。由于其形状记忆效应和超弹性特性,它被广泛应用于医疗领域,代表了智能材料的未来发展方向。随着医疗介入领域的发展,镍钛合金在血管介入医疗器械中的优势因其卓越的性能而日益得到认可,并引起了广泛关注。因此,需要对其医疗应用进行分析,以促进跨学科整合。本综述总结了镍钛合金作为血管介入医疗器械的结构特性、制备方法和应用领域。此外,还分析了镍钛合金在特定情况下用作支架或导线时的性能,并讨论了当前的不足、未来的发展方向和应用前景。
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Application and progress of NiTi alloys in vascular interventional medical devices
Nowadays there has been a substantial escalation in the consumption of the global annual mortality rate due to cardiovascular and cerebrovascular diseases, and the traditional stainless-steel materials used for interventional treatments are sometimes unsuitable for thinner vascular walls. Hence it is imperative to undertake a comprehensive analysis of novel materials in the field of vascular intervention, and NiTi alloys are one of the best materials among them. NiTi alloys are the shape-memory alloys that undergo a phase transformation under certain temperatures and pressures. Owing to its shape memory effect and superelastic properties, it is extensively utilized in the medical filed, representing a future direction for smart materials. As the field of medical intervention evolves, the advantages of NiTi alloys in vascular interventional medical devices are increasingly recognized due to their superior performance, garnering widespread attention. As a result, analyzing their medical applications is required in order to promote interdisciplinary integration. This review summarizes the structural properties, preparation methods, and application areas of NiTi alloys as medical devices for vascular interventions. It also analyzes the properties of NiTi alloys when used as stents or guidewires in specific scenarios, and discusses the current shortcomings, future development directions and application prospects.
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