印度中部前瞻性人口登记中使用外阴切开术的趋势和决定因素

IF 2.8 2区 医学 Q1 OBSTETRICS & GYNECOLOGY BMC Pregnancy and Childbirth Pub Date : 2024-09-12 DOI:10.1186/s12884-024-06762-y
Kirsten E. Austad, Sowmya R. Rao, Patricia L. Hibberd, Archana B. Patel
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引用次数: 0

摘要

研究结果和世界卫生组织的建议倾向于限制使用外阴切开术,但印度是否遵循了这一指导以及与使用外阴切开术相关的因素尚不清楚。本研究试图记录五年内(2014-2018 年)外阴切开术的使用趋势;研究其与产妇、妊娠和医疗系统特征的关系;并调查其与其他产科干预措施的关联。我们对产妇新生儿健康登记处收集的数据进行了二次分析,该登记处是在印度中部(马哈拉施特拉邦东部的那格浦尔)建立的一个基于人口的前瞻性妊娠登记处。我们通过多变量泊松回归模型研究了2014年至2018年的分娩类型和阴道分娩中外阴切开术的使用情况,以及产妇和分娩特征、卫生系统因素和同时进行的产科干预与外阴切开术使用的相关性。在这五年间,尽管阴道助产率有所下降,但阴道分娩中的外阴切开术率却从13%上升到31%。发现以下因素与外阴切开术有关:先兆流产、多胎妊娠、产妇受教育年限为 7 年或以上、胎龄较高、出生体重较高、由产科医生接生(与助产士或普通医生相比)以及在医院分娩(与诊所或保健中心相比)。在对这些因素进行调整后,外阴切开术的逐年上升是显著的,调整后的发病率比(AIRR)为 1.10 [95% 置信区间 (CI) 1.08-1.12;P = 0.002]。我们发现外阴切开术与其他几种产科干预措施之间存在关联,其中与产妇使用抗生素治疗的关系最为密切(AIRR 4.23,95% CI 3.12-5.73;P = 0.001)。从 2014 年到 2018 年,印度中部人口样本中的外阴切开术稳步上升。即使在调整了患者特征、产科风险因素和医疗系统特征(如分娩提供者的专业性)后,也观察到了这种随时间推移的增长。鉴于大多数产妇更愿意避免外阴切开术,我们的研究结果对母婴健康和尊重产妇的护理具有重要意义;研究结果还强调了抗生素管理的潜在目标,这是全球抗菌药耐药性防治工作的一部分。该研究已在临床试验网(ClinicalTrials.gov)注册,编号为NCT01073475。外阴切开术是一种为分娩扩大阴道口的外科手术。外阴切开术曾经在全球范围内被普遍使用。然而,由于该手术会给产妇带来疼痛,并使她们面临感染和阴道严重撕裂的风险,特别是当切口直接向下时,研究表明应尽量少用。因此,现在高收入国家已较少采用这种方法,但印度是否也是如此尚不清楚。为了回答这个问题,我们使用了印度中部(那格浦尔)的一个大型人口妊娠登记系统--孕产妇新生儿健康登记系统,以评估 2014 年至 2018 年期间外阴切开术的使用频率,以及是否存在与外阴切开术使用相关的某些孕产妇特征、医疗保健系统特征和其他妊娠干预措施。在这五年间,阴道分娩时外阴切开术的使用率上升了两倍多。外阴切开术更多地用于从未分娩过、怀孕时间较长、受教育程度较高、胎儿较重或怀有一个以上胎儿的产妇。与助产士或普通医生相比,产科医生更有可能实施外阴切开术,而且医院比诊所或初级保健中心更有可能实施这种手术。即使考虑到这些患者和医疗服务提供者的特征,五年间的这种上升趋势也是显著的,这表明医疗实践发生了转变。由于这是一项观察性研究,因此还需要更多的研究来确定我们发现的关联是否是因果关系。
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Trends and determinants of the use of episiotomy in a prospective population-based registry from central India
Findings from research and recommendations from the World Health Organization favor restrictive use of episiotomy, but whether this guidance is being followed in India, and factors associated with its use, are not known. This study sought to document trends in use of episiotomy over a five-year period (2014–2018); to examine its relationship to maternal, pregnancy, and health-system characteristics; and to investigate its association with other obstetric interventions. We conducted a secondary analysis of data collected by the Maternal Newborn Health Registry, a prospective population-based pregnancy registry established in Central India (Nagpur, Eastern Maharashtra). We examined type of birth and use of episiotomy in vaginal deliveries from 2014 to 2018, as well as maternal and birth characteristics, health systems factors, and concurrent obstetric interventions associations with its use with multivariable Poisson regression models. During the five-year interval, the rate of episiotomy in vaginal birth rose from 13 to 31% despite a decline in assisted vaginal birth. Associations with episiotomy were found for the following factors: prior birth, multiple gestations, seven or more years of maternal education, higher gestational age, higher birthweight, delivery by an obstetrician (as compared to midwife or general physician), and birth in hospital (as compared to clinic or health center). After adjusting for these factors, year over year rise in episiotomy was significant with an adjusted incidence rate ratio (AIRR) of 1.10 [95% confidence interval (CI) 1.08–1.12; p = 0.002]. We found an association between episiotomy and several other obstetric interventions, with the strongest relationship for maternal treatment with antibiotics (AIRR 4.23, 95% CI 3.12–5.73; p = 0.001). Episiotomy in this population-based sample from central India steadily rose from 2014 to 2018. This increase over time was observed even after adjusting for patient characteristics, obstetric risk factors, and health system features, such as specialty of the birthing provider. Our findings have important implications for maternal-child health and respectful maternity care given that most women prefer to avoid episiotomy; they also highlight a potential target for antibiotic stewardship as part of global efforts to combat antimicrobial resistance. The study was registered at ClinicalTrials.gov under reference number NCT01073475. Episiotomy is a surgical procedure to widen the vaginal opening for childbirth. It was once commonly used worldwide. However, because the procedure can cause pain to mothers and place them at risk for infections and serious tears to the vagina—especially when the cut is directly downward—research suggests it should be used sparingly. As such, it is now less often practiced in high-income countries, but whether the same is true in India is not known. To answer this question, we used a large population-based pregnancy registry, the Maternal Newborn Health Registry, from Central India (Nagpur) to assess the frequency of episiotomy use between 2014 and 2018 and if there were certain maternal characteristics, features of the health care system, and other pregnancy interventions that were related with its use. Over this five-year period, the use of episiotomy during vaginal birth rose more than two-fold. It was more often used on women who had never delivered a baby before, were further along in pregnancy, had higher levels of education, had heavier babies, or were carrying more than one baby. Obstetricians were more likely to perform episiotomy than midwives or general physicians and it was more likely to be performed in hospitals than in clinics or primary health centers. This rise during the five-year interval was significant even when accounting for these patient and provider characteristics, suggesting a shift in medical practice. Because this was an observational study more research is needed to determine if the associations we found are causal.
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来源期刊
BMC Pregnancy and Childbirth
BMC Pregnancy and Childbirth OBSTETRICS & GYNECOLOGY-
CiteScore
4.90
自引率
6.50%
发文量
845
审稿时长
3-8 weeks
期刊介绍: BMC Pregnancy & Childbirth is an open access, peer-reviewed journal that considers articles on all aspects of pregnancy and childbirth. The journal welcomes submissions on the biomedical aspects of pregnancy, breastfeeding, labor, maternal health, maternity care, trends and sociological aspects of pregnancy and childbirth.
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