Wesam H. Khalaf, Subhi A. Al-Jibori, Muhammad Ashfaq, Ahmed S. Faihan, Muhammad Nawaz Tahir, Ahmed S. M. Al-Janabi
{"title":"钯（II）和铂（II）-2H-苯并[e][1,3]恶嗪-2,4(3H)-二酮（HBzoxe）配合物的合成、表征和生物活性研究","authors":"Wesam H. Khalaf, Subhi A. Al-Jibori, Muhammad Ashfaq, Ahmed S. Faihan, Muhammad Nawaz Tahir, Ahmed S. M. Al-Janabi","doi":"10.1007/s11696-024-03650-9","DOIUrl":null,"url":null,"abstract":"<div><p>Mixed-ligand complexes of Pd(II) and Pt(II) with 2H-benzo[e][1,3] oxazine-2,4(3H)-dione (HBzoxe), tertiary phosphines (dppe, dppp, dppf and Ph<sub>3</sub>P), 2,2′-bipyridine (Bipy) and 1,10-phenanthroline (Phen) have been synthesized and characterized by molar conductance measurements, elemental analysis, IR and NMR (<sup>1</sup>H, <sup>13</sup>C and <sup>31</sup>P) spectroscopy. In addition, the antimicrobial activity assay studies. The results showed that the HBzoxe ligand behaves as a bidentate chelation ligand through the O and N atoms in [M(Bzoxe)<sub>2</sub>] {M<sup>II</sup> = Pd(<b>1</b>) and Pt(<b>2</b>)} complexes, whereas it acts as monodentate ligand through the oxygen atom in complexes (<b>3–14</b>) to afford a square planner geometry around Pd(II) and Pt(II) for all of the complexes. All of the complexes were moderately active on all the bacteria tested (<i>Staphylococcus aureus</i> and<i> Escherichia coli</i>). Hirshfeld surface analysis was carried out to investigate the cooperative non-covalent supramolecular interactions within the various complexes.</p></div>","PeriodicalId":513,"journal":{"name":"Chemical Papers","volume":"78 14","pages":"7987 - 7998"},"PeriodicalIF":2.2000,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Synthesis, characterization and biological activity studies of Pd(II) and Pt(II)–2H-benzo[e][1,3]oxazine-2,4(3H)-dione (HBzoxe) complexes\",\"authors\":\"Wesam H. Khalaf, Subhi A. Al-Jibori, Muhammad Ashfaq, Ahmed S. Faihan, Muhammad Nawaz Tahir, Ahmed S. M. Al-Janabi\",\"doi\":\"10.1007/s11696-024-03650-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Mixed-ligand complexes of Pd(II) and Pt(II) with 2H-benzo[e][1,3] oxazine-2,4(3H)-dione (HBzoxe), tertiary phosphines (dppe, dppp, dppf and Ph<sub>3</sub>P), 2,2′-bipyridine (Bipy) and 1,10-phenanthroline (Phen) have been synthesized and characterized by molar conductance measurements, elemental analysis, IR and NMR (<sup>1</sup>H, <sup>13</sup>C and <sup>31</sup>P) spectroscopy. In addition, the antimicrobial activity assay studies. The results showed that the HBzoxe ligand behaves as a bidentate chelation ligand through the O and N atoms in [M(Bzoxe)<sub>2</sub>] {M<sup>II</sup> = Pd(<b>1</b>) and Pt(<b>2</b>)} complexes, whereas it acts as monodentate ligand through the oxygen atom in complexes (<b>3–14</b>) to afford a square planner geometry around Pd(II) and Pt(II) for all of the complexes. All of the complexes were moderately active on all the bacteria tested (<i>Staphylococcus aureus</i> and<i> Escherichia coli</i>). Hirshfeld surface analysis was carried out to investigate the cooperative non-covalent supramolecular interactions within the various complexes.</p></div>\",\"PeriodicalId\":513,\"journal\":{\"name\":\"Chemical Papers\",\"volume\":\"78 14\",\"pages\":\"7987 - 7998\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-08-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Papers\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s11696-024-03650-9\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Engineering\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Papers","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s11696-024-03650-9","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Engineering","Score":null,"Total":0}
Synthesis, characterization and biological activity studies of Pd(II) and Pt(II)–2H-benzo[e][1,3]oxazine-2,4(3H)-dione (HBzoxe) complexes
Mixed-ligand complexes of Pd(II) and Pt(II) with 2H-benzo[e][1,3] oxazine-2,4(3H)-dione (HBzoxe), tertiary phosphines (dppe, dppp, dppf and Ph3P), 2,2′-bipyridine (Bipy) and 1,10-phenanthroline (Phen) have been synthesized and characterized by molar conductance measurements, elemental analysis, IR and NMR (1H, 13C and 31P) spectroscopy. In addition, the antimicrobial activity assay studies. The results showed that the HBzoxe ligand behaves as a bidentate chelation ligand through the O and N atoms in [M(Bzoxe)2] {MII = Pd(1) and Pt(2)} complexes, whereas it acts as monodentate ligand through the oxygen atom in complexes (3–14) to afford a square planner geometry around Pd(II) and Pt(II) for all of the complexes. All of the complexes were moderately active on all the bacteria tested (Staphylococcus aureus and Escherichia coli). Hirshfeld surface analysis was carried out to investigate the cooperative non-covalent supramolecular interactions within the various complexes.
Chemical PapersChemical Engineering-General Chemical Engineering
CiteScore
3.30
自引率
4.50%
发文量
590
期刊介绍：
Chemical Papers is a peer-reviewed, international journal devoted to basic and applied chemical research. It has a broad scope covering the chemical sciences, but favors interdisciplinary research and studies that bring chemistry together with other disciplines.
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