使用肿瘤坏死因子抑制剂的炎症性肠病患者罹患矛盾性类风湿性关节炎的风险：倾向匹配多中心研究

IF 4.5 3区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY Inflammatory Bowel Diseases Pub Date : 2024-09-11 DOI:10.1093/ibd/izae203

Akash Keluth Chavan, Pankhuri Jha, Jaime Abraham Perez, Elleson Harper, Preetika Sinh, Gregory Cooper, Jeffry Katz, Fabio Cominelli, Miguel Regueiro, Emad Mansoor

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引用次数: 0

摘要

摘要肿瘤坏死因子（TNF）抑制剂治疗炎症性肠病（IBD）与类风湿性关节炎和其他炎症性疾病的风险增加有关。我们的回顾性研究显示，与非抗 TNF 治疗 IBD 相比，风险并没有增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Risk of Paradoxical Rheumatoid Arthritis in Inflammatory Bowel Disease Patients Exposed to Tumor Necrosis Factor Inhibitors: A Propensity-Matched Multicenter Study

Lay Summary Tumor necrosis factor (TNF) inhibitor therapy for inflammatory bowel disease (IBD) has been associated with an increased risk of rheumatoid arthritis and other inflammatory conditions. Our retrospective study did not show an increased risk when compared with non-anti-TNF therapy for IBD.

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来源期刊

Inflammatory Bowel Diseases 医学-胃肠肝病学

CiteScore

9.70

自引率

6.10%

发文量

462

审稿时长

1 months

期刊介绍： Inflammatory Bowel Diseases® supports the mission of the Crohn''s & Colitis Foundation by bringing the most impactful and cutting edge clinical topics and research findings related to inflammatory bowel diseases to clinicians and researchers working in IBD and related fields. The Journal is committed to publishing on innovative topics that influence the future of clinical care, treatment, and research.