风湿病学随机对照试验中女性作者的趋势和影响:对 2009 年至 2023 年所有已发表随机对照试验的全面分析

Kim Lauper, Diana Buitrago-Garcia, Delphine Sophie Courvoisier, Michele Iudici, Denis Mongin
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引用次数: 0

摘要

研究目的本研究旨在探讨风湿病学领域发表的随机对照试验(RCT)中女性作者的演变情况和影响因素:本研究纳入了 2009 年至 2023 年间发表的所有风湿病学 RCT。作者的性别是通过性别 API 服务使用姓氏和所属国家确定的。使用广义估计方程评估了RCT论文中女性的比例及其与潜在因素的关系,将女性性别作为主要的二元结果,并将RCT的洲别、国际合作状况、工业资助、干预类型、样本大小、期刊是否符合ICMJE建议、影响因子、发表年份、作者的非学术附属机构和作者职位作为协变量。研究结果在 10,794 人撰写的 1,092 篇 RCT 中,女性作者占 34.1%。与北美相比,在非洲的 RCT 中,当作者为非学术界人士和最后一位作者为女性时,女性作者的比例更高(1.83 [1.46, 2.29], +6.1个百分点 - pp)。在亚洲和欧洲的 RCT 以及工业资助的 RCT 中,女性作者的比例较低(OR 0.64 [0.56-0.73];-10.3pp)。女性在最后一位作者(0.63 [0.54-0.74]; -10.2pp)和倒数第二位作者(0.73 [0.62-0.85]; -7.3pp)中的比例较低。国际地位和发表年份没有差异。结论女性作者的总体比例为 34.1%。女性在 RCT 中的代表性逐年停滞不前,而且女性担任高级作者的可能性较低,这突出表明需要采取更有效的策略来缩小性别差距。有女性最后作者的 RCT 更有可能有女性第一作者,这表明潜在的榜样效应。
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Trends and Influences in women authorship of randomized controlled trials in rheumatology: a comprehensive analysis of all published RCTs from 2009 to 2023
Objectives: This study aims to examine the evolution and influencing factors of women's authorship in randomized controlled trials (RCTs) published in rheumatology. Methods: This study included all rheumatology RCTs published from 2009 to 2023. The gender of authors was determined using forenames and countries of affiliation via the gender API service. The percentage of women in RCT publications and its association with potential factors was assessed using generalized estimating equations, considering women gender as the main binary outcome and the RCT's continent, international collaboration status, industrial funding, intervention type, sample size, journal adherence to ICMJE recommendations, impact factor, publication year, author's non-academic affiliation, and author position as covariates. Results: Among the 1,092 RCTs authored by 10,794 persons, women accounted for 34.1% of authors. Woman authorship was more frequent in African-based RCTs compared to North America, when the author had a non-academic affiliation and when the last author was a woman (1.83 [1.46, 2.29], +6.1 percentage points - pp). Woman authorship was less frequent in Asian and European-based RCTs, industry-funded RCTs (OR 0.64 [0.56-0.73]; -10.3pp). Women were less often in the last (0.63 [0.54-0.74]; -10.2 pp) and second to last author position (0.73 [0.62-0.85]; -7.3pp). There were no difference looking at international status or year of publication. Conclusion: The overall presence of women authors was 34.1%. The stagnant year-over-year representation of women in RCTs, and the lower likelihood of a woman having a position as senior author, underscores the need for more effective strategies to bridge the gender gap. RCTs with a woman last author were more likely to have a woman first author, suggesting a potential role-model effect.
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