继 2019-2020 年有针对性的大规模预防运动之后,2022 年刚果民主共和国戈马的口服霍乱疫苗覆盖率

IF 2.7 Q3 IMMUNOLOGY Vaccine: X Pub Date : 2024-09-12 DOI:10.1016/j.jvacx.2024.100555
Emily Briskin , Stéphane Hans Bateyi Mustafa , Rachel Mahamba , Deka Kabunga , Janvier Kubuya , Klaudia Porten , Epicentre-MSF DRC cholera working group, Laurent Akilimali , Placide Okitayemba Welo , Anaïs Broban
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引用次数: 0

摘要

背景2019-2020年,在刚果民主共和国戈马的24/32个非毗邻卫生区开展了预防性口服霍乱疫苗接种活动。2022年8月,我们对覆盖率和可能影响接种策略成功与否的因素进行了测量。方法我们采用随机地理抽样分层群组调查来估算霍乱口服疫苗的覆盖率,并评估人口流动、腹泻史和不接种疫苗的原因。至少接种一剂疫苗的覆盖率为 46.4%(95 %CI:41.8-51.0),接种目标地区为 50.1%(95 %CI:45.4-54.8),非目标地区为 26.3%(95 %CI:19.2-34.9)。此外,7.0%的参与者报告自2019年以来从戈马以外地区搬迁,5.4%的参与者报告有严重腹泻病史。缺席和不了解是未接种疫苗的主要原因。针对整个地理上毗邻的地区、调整分发方式和定期补种活动是本研究提出的提高覆盖率的操作建议。
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Oral cholera vaccine coverage in Goma, Democratic Republic of the Congo, 2022, following 2019–2020 targeted preventative mass campaigns

Background

In 2019–2020, preventative Oral Cholera Vaccine campaigns were conducted in 24/32 non-contiguous health areas of Goma, DR Congo. In August 2022, we measured coverage and factors potentially influencing success of the delivery strategy.

Methods

We used random geo-sampled stratified cluster survey to estimate OCV coverage and assess population movement, diarrhea history, and reasons for non-vaccination.

Results

603 households were visited. Coverage with at least one dose was 46.4 % (95 %CI: 41.8–51.0), and 50.1 % (95 %CI: 45.4–54.8) in areas targeted by vaccination compared to 26.3 % (95 %CI: 19.2–34.9) in non-targeted areas. Additionally, 7.0 % of participants reported moving from outside Goma since 2019, and 5.4 % reported history of severe diarrhea. Absence and unawareness were the main reasons for non-vaccination.

Conclusion

Results suggest that targeting non-contiguous urban areas had a coverage-diluting effect. Targeting entire geographically contiguous areas, adapted distribution, and regular catch-up campaigns are operational recommendations to reach higher coverages arising from the study.

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来源期刊
Vaccine: X
Vaccine: X Multiple-
CiteScore
2.80
自引率
2.60%
发文量
102
审稿时长
13 weeks
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