神经系统疾病中特异性促溶解介质的机制和功能研究进展

IF 2.5 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Prostaglandins & other lipid mediators Pub Date : 2024-09-10 DOI:10.1016/j.prostaglandins.2024.106905
Yu Deng , Fei Wang , Tianle Wang , Xu Zhang , Du Chen , Yuhan Wang , Chaojun Chen , Guangtao Pan
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引用次数: 0

摘要

神经系统通过各种细胞调节器、信号通路和分子机制与免疫系统相互作用。这些相互作用的中断会导致多种神经系统疾病的发生。最近的研究发现,特异性促溶解介质(SPMs)在神经免疫系统中发挥着调节作用。本研究回顾了有关 SPMs 在炎症过程中的功能及其与神经系统的关系的最新研究。该综述旨在为研究神经系统疾病的发病机制提供新的视角,并为临床治疗确定新的靶点。
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Research progress in the mechanisms and functions of specialized pro-resolving mediators in neurological diseases

The nervous system interacts with the immune system through a variety of cellular regulators, signaling pathways, and molecular mechanisms. Disruptions in these interactions lead to the development of multiple neurological diseases. Recent studies have identified that specialized pro-resolving mediators (SPMs) play a regulatory role in the neuroimmune system. This study reviews recent research on the function of SPMs in the inflammatory process and their association with the nervous system. The review aims to provide new perspectives for studying the pathogenesis of neurological diseases and identify novel targets for clinical therapy.

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来源期刊
Prostaglandins & other lipid mediators
Prostaglandins & other lipid mediators 生物-生化与分子生物学
CiteScore
5.80
自引率
3.40%
发文量
49
审稿时长
2 months
期刊介绍: Prostaglandins & Other Lipid Mediators is the original and foremost journal dealing with prostaglandins and related lipid mediator substances. It includes basic and clinical studies related to the pharmacology, physiology, pathology and biochemistry of lipid mediators. Prostaglandins & Other Lipid Mediators invites reports of original research, mini-reviews, reviews, and methods articles in the basic and clinical aspects of all areas of lipid mediator research: cell biology, developmental biology, genetics, molecular biology, chemistry, biochemistry, physiology, pharmacology, endocrinology, biology, the medical sciences, and epidemiology. Prostaglandins & Other Lipid Mediators also accepts proposals for special issue topics. The Editors will make every effort to advise authors of the decision on the submitted manuscript within 3-4 weeks of receipt.
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