导电聚合物中的磁感应加热技术在生物医学中的应用

IF 15.8 1区 材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY ACS Nano Pub Date : 2024-09-16 DOI:10.1021/acsnano.4c04717
Zhihui Lei, Shun Chen, Yu Liao, Wendong Liu, Lian Zhou, Benwei Fu, Peng Tao, Wen Shang, Jie Liu, Cuilan Hou, Chengyi Song, Tao Deng
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引用次数: 0

摘要

在本研究中,我们研究了在替代磁场(AMF)下导电聚合物(CP)中诱导的磁感应加热。实验结果和数值模拟证明,导电聚合物的磁热转换是由诱导涡流引起的,而诱导涡流与外加 AMF 的形状和强度以及导电聚合物的固有电导率、宏观结构和微观结构有关。通过采用各种制造方法,可以在导电聚合物薄膜和气凝胶中实现特定的温度分布和热场控制。为了挖掘 CP 中磁感应加热在生物医学应用中的潜力,我们设计了一种基于导电聚合物气凝胶的自适应热贴片,并演示了其在 AMF 作用下对皮肤的局部加热。除了通过 CP 的磁热转换对肿瘤细胞进行热消融外,通过无创磁电刺激在温和温度下促进神经元分化也被证明是一种有效的组织工程策略。
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Magnetic Induction Heating in a Conducting Polymer for Biomedical Applications
In this study, we investigate the magnetic induction heating induced in a conducting polymer (CP) under alternative magnetic fields (AMFs). Experimental results and numerical simulations have proved that the magneto-thermal conversion of the CP is caused by the induced eddy current, which is related to the shape and intensity of the applied external AMF, and the intrinsic electrical conductivity, macrostructure and microstructure of the CP. By employing various fabrication methods, specific temperature distribution and control of thermal field within conducting polymer films and aerogels could be achieved. To exploit the potential of magnetic induction heating in CP for biomedical applications, we designed a conducting polymer aerogel-based self-adaptive heat patch and demonstrated its AMF-enabled localized heating of skin. In addition to the thermal ablation of tumor cells via magneto-thermal conversion of the CP, the promotion of neuronal differentiation at mild temperature by noninvasive magneto-electrical stimulation has also been demonstrated to be an effective strategy for tissue engineering.
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来源期刊
ACS Nano
ACS Nano 工程技术-材料科学:综合
CiteScore
26.00
自引率
4.10%
发文量
1627
审稿时长
1.7 months
期刊介绍: ACS Nano, published monthly, serves as an international forum for comprehensive articles on nanoscience and nanotechnology research at the intersections of chemistry, biology, materials science, physics, and engineering. The journal fosters communication among scientists in these communities, facilitating collaboration, new research opportunities, and advancements through discoveries. ACS Nano covers synthesis, assembly, characterization, theory, and simulation of nanostructures, nanobiotechnology, nanofabrication, methods and tools for nanoscience and nanotechnology, and self- and directed-assembly. Alongside original research articles, it offers thorough reviews, perspectives on cutting-edge research, and discussions envisioning the future of nanoscience and nanotechnology.
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