Ramya Ayyalasomayajula, Ivet Boneva, David Ormaza, Andrew Whyte Jr., Kamran Farook, Zachary Gorlin, Evelyn Yancey, Sabine André, Herbert Kaltner, Maré Cudic
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Cover Feature: Synthesis and Thermodynamic Evaluation of Sialyl-Tn MUC1 Glycopeptides Binding to Macrophage Galactose-Type Lectin (ChemBioChem 18/2024)
Isothermal titration calorimetry (ITC) analysis of the binding of hMGL to Tn and sialyl-Tn MUC1 glycopeptides revealed a dynamic process in which lectin molecules bind to carbohydrate ligands and jump from ligand to ligand along the glycopeptides’ backbone. More details can be found in article 10.1002/cbic.202400391 by Maré Cudic and co-workers.
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ChemBioChem (Impact Factor 2018: 2.641) publishes important breakthroughs across all areas at the interface of chemistry and biology, including the fields of chemical biology, bioorganic chemistry, bioinorganic chemistry, synthetic biology, biocatalysis, bionanotechnology, and biomaterials. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies, and supported by the Asian Chemical Editorial Society (ACES).
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