Jan M. Kurzyna, Rafał J. Kopiasz, Martyna Paul, Magdalena Flont, Patrycja Baranowska, Jolanta Mierzejewska, Karolina Drężek, Waldemar Tomaszewski, Elżbieta Jastrzębska, Dominik Jańczewski
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Unlocking the Potential: PEGylation and Molecular Weight Reduction of Ionenes for Enhanced Antifungal Activity and Biocompatibility
Back Cover: Synthetic polymers mimicking antimicrobial peptides show potent activity but high toxicity. This study's cationic ionenes, modified with a PEG side chain, exhibited high antimicrobial activity and reduced toxicity. Remarkably, lower molecular weight increased antifungal activity, with MICs as low as 2 and 0.0625 µg/mL for C. albicans and C. tropicalis. More details can be found in article 2400032 by Dominik Jańczewski and co-workers.
期刊介绍：
Macromolecular Bioscience is a leading journal at the intersection of polymer and materials sciences with life science and medicine. With an Impact Factor of 2.895 (2018 Journal Impact Factor, Journal Citation Reports (Clarivate Analytics, 2019)), it is currently ranked among the top biomaterials and polymer journals.
Macromolecular Bioscience offers an attractive mixture of high-quality Reviews, Feature Articles, Communications, and Full Papers.
With average reviewing times below 30 days, publication times of 2.5 months and listing in all major indices, including Medline, Macromolecular Bioscience is the journal of choice for your best contributions at the intersection of polymer and life sciences.
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