Ephrasia A. Hugho, Blandina T. Mmbaga, Abdul-Hamid S. Lukambagire, Grace D. Kinabo, Kate M. Thomas, Happiness H. Kumburu, Tine Hald
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引用次数: 0
摘要
沙门氏菌是全球腹泻的致病菌之一,但人们对其在坦桑尼亚儿童中的风险因素知之甚少。2020 年 7 月至 2022 年 11 月,我们在乞力马扎罗地区的莫希市开展了一项基于医院的横断面研究,研究对象是因腹泻住院的五岁以下儿童。研究人员向所有入选儿童的父母/监护人发放了调查问卷。采用逻辑回归法分析风险因素,显著性为 p <0.05。共有 306 名儿童参与了研究。年龄中位数为 13.8 个月(IQR 8.4-21.8)。大多数(58.5%)为男性,59.5%来自农村地区。在 8 份(2.6%)粪便样本中发现了沙门氏菌,城市地区的发病率高于农村地区(4.8% 对 1.1%;P 值 = 0.044)。与儿童感染沙门氏菌相关的重要风险因素包括饮用生牛奶(调整后 OR = 30.19;95% CI:3.94-231.46)、使用婴儿配方奶粉(调整后 OR = 15.78;95% CI:2.98-83.56)、未披露家庭情况(调整后 OR = 30.19;95% CI:3.94-231.46)。56)、未披露家庭收入(调整 OR = 9.98;95% CI:2.46-40.12)、直接从农场购买鸡蛋(调整 OR = 7.58;95% CI:1.31-43.96)以及与鸡接触(调整 OR = 6.49;95% CI:1.25-33.59)。这些发现突出表明,有必要采取有针对性的干预措施,以改善食品安全、卫生习惯和社会经济条件。
Risk Factors for Salmonella Infection in Children under Five Years: A Hospital-Based Study in Kilimanjaro Region, Tanzania
Salmonella is among the causative agents for diarrhea worldwide, but its risk factors in Tanzanian children are poorly understood. A hospital-based cross-sectional study was conducted in Moshi, Kilimanjaro region, from July 2020 to November 2022 among children under five admitted with diarrhea. A questionnaire was administered to all parents/caretakers of the enrolled children. Logistic regression was utilized to analyze the risk factors, with significance at p < 0.05. A total of 306 children were enrolled in the study. The median age was 13.8 months (IQR 8.4–21.8). The majority (58.5%) were males, and 59.5% were from rural areas. Salmonella was identified in eight (2.6%) stool samples, with a higher prevalence in urban than rural areas (4.8% vs. 1.1%; p-value = 0.044). The significant risk factors associated with Salmonella infection among the children included consuming raw milk (adjusted OR = 30.19; 95% CI: 3.94–231.46), using infant formula (adjusted OR = 15.78; 95% CI: 2.98–83.56), undisclosed household income (adjusted OR = 9.98; 95% CI: 2.46–40.12), purchasing eggs direct from the farms (adjusted OR = 7.58; 95%CI: 1.31–43.96), and contact with chickens (adjusted OR = 6.49; 95%CI: 1.25–33.59). These findings highlight the need for targeted interventions to improve food safety, hygiene practices, and socioeconomic conditions.
期刊介绍:
Pathogens (ISSN 2076-0817) publishes reviews, regular research papers and short notes on all aspects of pathogens and pathogen-host interactions. There is no restriction on the length of the papers. Our aim is to encourage scientists to publish their experimental and theoretical research in as much detail as possible. Full experimental and/or methodical details must be provided for research articles.