人血清白蛋白与磷酸盐和特里斯缓冲液的相互作用:对紫杉醇结合和纳米颗粒自组装的影响

IF 3 4区 医学 Q2 CHEMISTRY, APPLIED Journal of microencapsulation Pub Date : 2024-09-13 DOI:10.1080/02652048.2024.2389135
A. H. Gonzalez-Posada, M. Mesa, L. Sierra, B. Lopez
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引用次数: 0

摘要

研究人血清白蛋白(HSA)在pH值为7.4和9.9时因化学变性(CD)和热变性(TD)引起的构象变化。
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Interactions of human serum albumin with phosphate and Tris buffers: impact on paclitaxel binding and nanoparticles self-assembly
To investigate the conformational changes in human serum albumin (HSA) caused by chemical (CD) and thermal denaturation (TD) at pH 7.4 and 9.9, crucial for designing controlled drug delivery system...
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来源期刊
Journal of microencapsulation
Journal of microencapsulation 工程技术-工程:化工
CiteScore
6.30
自引率
2.60%
发文量
39
审稿时长
3 months
期刊介绍: The Journal of Microencapsulation is a well-established, peer-reviewed journal dedicated to the publication of original research findings related to the preparation, properties and uses of individually encapsulated novel small particles, as well as significant improvements to tried-and-tested techniques relevant to micro and nano particles and their use in a wide variety of industrial, engineering, pharmaceutical, biotechnology and research applications. Its scope extends beyond conventional microcapsules to all other small particulate systems such as self assembling structures that involve preparative manipulation. The journal covers: Chemistry of encapsulation materials Physics of release through the capsule wall and/or desorption from carrier Techniques of preparation, content and storage Many uses to which microcapsules are put.
期刊最新文献
Leflunomide nanocarriers: a new prospect of therapeutic applications. A comprehensive review on lipid-based nanoparticles via nose to brain targeting as a novel approach Interactions of human serum albumin with phosphate and Tris buffers: impact on paclitaxel binding and nanoparticles self-assembly The assessment of pharmacokinetics and neuroprotective effect of berberine hydrochloride-embedded albumin nanoparticles via various administration routes: comparative in-vivo studies in rats. Recent advancements in microspheres mediated targeted delivery for therapeutic interventions in osteoarthritis.
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