{"title":"用甲基化敏感型高分辨熔融法（MS-HRM）测定人血浆中的无细胞DNA（cfDNA）甲基化情况以诊断妊娠期糖尿病（GDM）","authors":"Zhiyu Liu, Yuwei Yang, Yunfei Bai, Qinyu Ge","doi":"10.1080/00032719.2024.2399182","DOIUrl":null,"url":null,"abstract":"Considerable interest has focused on cell-free DNA (cfDNA) methylation for noninvasive prenatal diagnosis. We investigated maternal plasma DNA methylation using a simple protocol. Eighty plasma sam...","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Determination of Cell-Free DNA (cfDNA) Methylation by Methylation-Sensitive High-Resolution Melting (MS-HRM) in Human Plasma for the Diagnosis of Gestational Diabetes Mellitus (GDM)\",\"authors\":\"Zhiyu Liu, Yuwei Yang, Yunfei Bai, Qinyu Ge\",\"doi\":\"10.1080/00032719.2024.2399182\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Considerable interest has focused on cell-free DNA (cfDNA) methylation for noninvasive prenatal diagnosis. We investigated maternal plasma DNA methylation using a simple protocol. Eighty plasma sam...\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-09-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/00032719.2024.2399182\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/00032719.2024.2399182","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
摘要
人们对用于无创产前诊断的无细胞 DNA（cfDNA）甲基化非常感兴趣。我们采用简单的方法研究了母体血浆 DNA 甲基化。80份血浆样本...
Determination of Cell-Free DNA (cfDNA) Methylation by Methylation-Sensitive High-Resolution Melting (MS-HRM) in Human Plasma for the Diagnosis of Gestational Diabetes Mellitus (GDM)
Considerable interest has focused on cell-free DNA (cfDNA) methylation for noninvasive prenatal diagnosis. We investigated maternal plasma DNA methylation using a simple protocol. Eighty plasma sam...
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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