Melissa J Martin, Ting L Luo, Valentyn Kovalchuk, Viacheslav Kondratiuk, Henry D Dao, Iryna Kovalenko, Brandon J Plaza, Joanna M Kettlewell, Cole P Anderson, Jason R Smedberg, Ana C Ong, Yoon I Kwak, Joshua S Hawley-Molloy, Jason W Bennett, Patrick T McGann, Francois Lebreton
{"title":"检测从乌克兰撤出的外国战斗人员中携带 blaNDM-5 和 blaKPC-3 的流行性大肠埃希菌 ST-361 对头孢羟氨苄和阿曲南类/阿维菌素的耐药性。","authors":"Melissa J Martin, Ting L Luo, Valentyn Kovalchuk, Viacheslav Kondratiuk, Henry D Dao, Iryna Kovalenko, Brandon J Plaza, Joanna M Kettlewell, Cole P Anderson, Jason R Smedberg, Ana C Ong, Yoon I Kwak, Joshua S Hawley-Molloy, Jason W Bennett, Patrick T McGann, Francois Lebreton","doi":"10.1128/aac.01090-24","DOIUrl":null,"url":null,"abstract":"<p><p>Genomic surveillance detected clonal <i>Escherichia coli</i> sequence type-361 isolates carrying <i>bla</i><sub>NDM-5</sub>, <i>bla</i><sub>KPC-3</sub>, <i>bla</i><sub>CTX-M-15</sub>, and <i>rmtB1</i> from a patient in Ukraine and four wounded foreign soldiers evacuated to Germany. Isolates were non-susceptible to carbapenems, aminoglycosides, and cefiderocol and aztreonam/avibactam due to a PBP3 YRIN insertion and the <i>bla</i><sub>CMY-145</sub> AmpC β-lactamase. Coordinated surveillance efforts across civilian, military, and veteran healthcare systems are essential to prevent further spread as international volunteers return home after medical evacuation from Ukraine.</p>","PeriodicalId":8152,"journal":{"name":"Antimicrobial Agents and Chemotherapy","volume":null,"pages":null},"PeriodicalIF":4.1000,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Detection of cefiderocol and aztreonam/avibactam resistance in epidemic <i>Escherichia coli</i> ST-361 carrying <i>bla</i><sub>NDM-5</sub> and <i>bla</i><sub>KPC-3</sub> from foreign fighters evacuated from Ukraine.\",\"authors\":\"Melissa J Martin, Ting L Luo, Valentyn Kovalchuk, Viacheslav Kondratiuk, Henry D Dao, Iryna Kovalenko, Brandon J Plaza, Joanna M Kettlewell, Cole P Anderson, Jason R Smedberg, Ana C Ong, Yoon I Kwak, Joshua S Hawley-Molloy, Jason W Bennett, Patrick T McGann, Francois Lebreton\",\"doi\":\"10.1128/aac.01090-24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Genomic surveillance detected clonal <i>Escherichia coli</i> sequence type-361 isolates carrying <i>bla</i><sub>NDM-5</sub>, <i>bla</i><sub>KPC-3</sub>, <i>bla</i><sub>CTX-M-15</sub>, and <i>rmtB1</i> from a patient in Ukraine and four wounded foreign soldiers evacuated to Germany. Isolates were non-susceptible to carbapenems, aminoglycosides, and cefiderocol and aztreonam/avibactam due to a PBP3 YRIN insertion and the <i>bla</i><sub>CMY-145</sub> AmpC β-lactamase. Coordinated surveillance efforts across civilian, military, and veteran healthcare systems are essential to prevent further spread as international volunteers return home after medical evacuation from Ukraine.</p>\",\"PeriodicalId\":8152,\"journal\":{\"name\":\"Antimicrobial Agents and Chemotherapy\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2024-09-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Antimicrobial Agents and Chemotherapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1128/aac.01090-24\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MICROBIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Antimicrobial Agents and Chemotherapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1128/aac.01090-24","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
Detection of cefiderocol and aztreonam/avibactam resistance in epidemic Escherichia coli ST-361 carrying blaNDM-5 and blaKPC-3 from foreign fighters evacuated from Ukraine.
Genomic surveillance detected clonal Escherichia coli sequence type-361 isolates carrying blaNDM-5, blaKPC-3, blaCTX-M-15, and rmtB1 from a patient in Ukraine and four wounded foreign soldiers evacuated to Germany. Isolates were non-susceptible to carbapenems, aminoglycosides, and cefiderocol and aztreonam/avibactam due to a PBP3 YRIN insertion and the blaCMY-145 AmpC β-lactamase. Coordinated surveillance efforts across civilian, military, and veteran healthcare systems are essential to prevent further spread as international volunteers return home after medical evacuation from Ukraine.
期刊介绍：
Antimicrobial Agents and Chemotherapy (AAC) features interdisciplinary studies that build our understanding of the underlying mechanisms and therapeutic applications of antimicrobial and antiparasitic agents and chemotherapy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
