呼吁海湾合作委员会 (GCC) 国家为 65 岁及以上的成年人接种大剂量流感疫苗。

IF 3.8 4区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Journal of Epidemiology and Global Health Pub Date : 2024-09-01 Epub Date: 2024-09-10 DOI:10.1007/s44197-024-00292-8
Salah T Al Awaidy, Parvaiz A Koul, Faryal Khamis, Fatima Al Slil, Imane Jroundi, Fatima Al Olama, Khalid Hamid Elawad, Musallam Yunus Hassan Abuhasan, Fana Al Oraimi, Mine Durusu Tanriover, Hassan Zaraket
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引用次数: 0

摘要

每年的季节性流感都会给全球的健康和经济带来重大挑战,尤其是对老年人口(年龄≥ 65 岁)的影响,住院率和死亡率都会上升。在海湾合作委员会(GCC)国家,老年人口正在稳步增长,并有可能进一步增加。此外,在这些国家,糖尿病和肥胖症等慢性并发症的负担很重,这增加了感染流感造成严重后果的可能性。海湾合作委员会国家还举办朝觐、Umrah 朝圣、Arba'een(伊拉克附近)朝圣以及国际体育和商业活动等大规模集会活动,这进一步加剧了流感等疾病爆发的风险。这些活动为来自不同国家的游客混杂在一起提供了便利。因此,北半球的流感活动通常在北半球季节性流感疫苗上市之前就已出现。这对老年人来说尤其棘手,因为他们上一年接种的疫苗对他们的保护作用已经减弱。曾有人使用较高剂量的抗原或佐剂来提高老年人的免疫原性,并取得了较好的疫苗效果。因此,有充分的理由支持在海湾合作委员会国家接种高剂量季节性流感疫苗,以加强对 65 岁及以上老年人的保护,使其免受流感感染和相关严重并发症的影响。
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A Call for Adopting High-Dose Influenza Vaccines for Adults Aged 65 and Above in Gulf Cooperation Council (GCC) Countries.

Seasonal influenza poses significant health and economic challenges globally each year, particularly impacting the elderly population (aged ≥ 65 years) with increased rates of hospitalization, and mortality. The population of older adults is steadily increasing in the Gulf Cooperation Council (GCC) countries and is likely to increase even further. In addition, there is a high burden of chronic comorbidities in these countries like diabetes and obesity, which increases the likelihood of severe consequences of influenza infection. The GCC countries also host mass gathering events like Hajj, Umrah pilgrimage, Arba'een (nearby Iraq) pilgrimage, and international sports and business events, which further intensify the risk of outbreaks like influenza. These events facilitate the mixing of visitors from various countries. Thus, influenza activity in this North Hemisphere (NH) geography is usually present even before the availability of NH seasonal influenza vaccine. This is especially problematic for the elderly, whose protection from the previous year's immunization would have waned. Higher dosages of antigens or adjuvants have been used to improve immunogenicity in older people with superior vaccine effectiveness. Therefore, there is a compelling argument in favor of the implementation of high-dose seasonal influenza vaccines in the GCC countries to improve the protection of individuals aged 65 years and older against influenza infection and associated severe complications.

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来源期刊
CiteScore
10.70
自引率
1.40%
发文量
57
审稿时长
19 weeks
期刊介绍: The Journal of Epidemiology and Global Health is an esteemed international publication, offering a platform for peer-reviewed articles that drive advancements in global epidemiology and international health. Our mission is to shape global health policy by showcasing cutting-edge scholarship and innovative strategies.
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